Shaw Joshua J, Santry Heena P
Department of Surgery and the Center for Outcomes Research-Surgical Research Scholars Program, University of Massachusetts Medical School, Worcester, MA.
Department of Surgery and the Center for Outcomes Research-Surgical Research Scholars Program, University of Massachusetts Medical School, Worcester, MA; Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA.
Chest. 2015 Nov;148(5):1242-1250. doi: 10.1378/chest.15-0576.
Although the benefits of early tracheostomy in patients dependent on ventilators are well established, the reasons for variation in time from intubation to tracheostomy remain unclear. We identified clinical and demographic disparities in time to tracheostomy.
We performed a level 3 retrospective prognostic study by querying the University HealthSystem Consortium (2007-2010) for adult patients receiving a tracheostomy after initial intubation. Time to tracheostomy was designated early (< 7 days) or late (> 10 days). Cohorts were stratified by time to tracheostomy and compared using univariate tests of association and multivariable adjusted models.
A total of 49,191 patients underwent tracheostomy after initial intubation: 42% early (n = 21,029) and 58% late (n = 28,162). On both univariate and multivariable analyses, women, blacks, Hispanics, and patients receiving Medicaid were less likely to receive an early tracheostomy. Patients in the early group also experienced lower rates of mortality (OR, 0.84; 95% CI, 0.79-0.88).
Early tracheostomy was associated with increased survival. Yet, there were still significant disparities in time to tracheostomy according to sex, race, and type of insurance. Application of evidence-based algorithms for tracheostomy may reduce unequal treatment and improve overall mortality rates. Additional research into this apparent bias in referral/rendering of tracheostomy is needed.
尽管早期气管切开术对依赖呼吸机的患者的益处已得到充分证实,但从插管到气管切开术的时间存在差异的原因仍不清楚。我们确定了气管切开术时间方面的临床和人口统计学差异。
我们通过查询大学卫生系统联盟(2007 - 2010年)中初次插管后接受气管切开术的成年患者进行了一项3级回顾性预后研究。气管切开术时间分为早期(<7天)或晚期(>10天)。根据气管切开术时间对队列进行分层,并使用单变量关联检验和多变量调整模型进行比较。
共有49191例患者在初次插管后接受了气管切开术:42%为早期(n = 21029),58%为晚期(n = 28162)。在单变量和多变量分析中,女性、黑人、西班牙裔以及接受医疗补助的患者接受早期气管切开术的可能性较小。早期组患者的死亡率也较低(OR,0.84;95%CI,0.79 - 0.88)。
早期气管切开术与生存率提高相关。然而,根据性别、种族和保险类型,气管切开术时间仍存在显著差异。应用基于证据的气管切开术算法可能会减少不平等治疗并提高总体死亡率。需要对气管切开术转诊/实施过程中这种明显的偏差进行更多研究。