通过β-咔啉导向的芳基环邻位C(sp(2))-H活化实现钯（乙酸）二催化的芳基（β-咔啉-1-基）甲酮的区域选择性烷氧基化反应。
Pd(OAc)2-catalysed regioselective alkoxylation of aryl (β-carbolin-1-yl)methanones via β-carboline directed ortho-C(sp(2))-H activation of an aryl ring.
作者信息
Kolle Shivalinga, Batra Sanjay
机构信息
Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow-226031, UP, India.
出版信息
Org Biomol Chem. 2015 Nov 7;13(41):10376-85. doi: 10.1039/c5ob01500f.
PMID:26324764
Abstract
Synthesis of (2-alkoxyphenyl)(9H-pyrido[3,4-b]indol-1-yl)methanone via Pd(OAc)2-catalyzed regioselective alkoxylation of aryl (β-carbolin-1-yl) methanones employing β-carboline directed ortho-C(sp(2))-H activation of an aryl ring under oxidative conditions is described.
摘要
描述了通过在氧化条件下利用β-咔啉导向的芳基环邻位C(sp(2))-H活化，由钯（II）乙酸盐催化芳基（β-咔啉-1-基）甲酮的区域选择性烷氧基化反应合成（2-烷氧基苯基）（9H-吡啶并[3,4-b]吲哚-1-基）甲酮。
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