干细胞重编程和分化过程中涉及的信号传导。
Signaling involved in stem cell reprogramming and differentiation.
作者信息
Tanabe Shihori
机构信息
Shihori Tanabe, National Institute of Health Sciences, Tokyo 158-8501, Japan.
出版信息
World J Stem Cells. 2015 Aug 26;7(7):992-8. doi: 10.4252/wjsc.v7.i7.992.
Abstract
Stem cell differentiation is regulated by multiple signaling events. Recent technical advances have revealed that differentiated cells can be reprogrammed into stem cells. The signals involved in stem cell programming are of major interest in stem cell research. The signaling mechanisms involved in regulating stem cell reprogramming and differentiation are the subject of intense study in the field of life sciences. In this review, the molecular interactions and signaling pathways related to stem cell differentiation are discussed.
摘要
干细胞分化受多种信号事件调控。最近的技术进展表明，分化细胞可被重编程为干细胞。参与干细胞编程的信号是干细胞研究的主要关注点。调控干细胞重编程和分化的信号机制是生命科学领域深入研究的课题。在本综述中，将讨论与干细胞分化相关的分子相互作用和信号通路。
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