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白癜风的替代全身治疗:综述

Alternative Systemic Treatments for Vitiligo: A Review.

作者信息

Cohen Brandon E, Elbuluk Nada, Mu Euphemia W, Orlow Seth J

机构信息

The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, 240 East 38th Street, New York, NY, 10016, USA.

出版信息

Am J Clin Dermatol. 2015 Dec;16(6):463-74. doi: 10.1007/s40257-015-0153-5.

DOI:10.1007/s40257-015-0153-5
PMID:26329814
Abstract

Vitiligo is a common, acquired disorder of skin pigmentation that can significantly impact quality of life. It often represents a therapeutic challenge, which has resulted in interest in alternative treatments such as herbal and vitamin supplements. In this review, we provide an overview of the most commonly studied complementary agents, describe proposed mechanisms of action, identify potential adverse effects, and discuss the primary evidence supporting their use. Our discussion focuses on L-phenylalanine, Polypodium leucotomos, khellin, Ginkgo biloba, and vitamins and minerals, including vitamins B12, C, and E, folic acid, and zinc used as monotherapy or in combination with other treatments for the management of vitiligo.

摘要

白癜风是一种常见的获得性皮肤色素沉着紊乱疾病,会对生活质量产生重大影响。它常常带来治疗挑战,这引发了人们对草药和维生素补充剂等替代疗法的兴趣。在本综述中,我们概述了最常研究的辅助药物,描述了其拟议的作用机制,确定了潜在的不良反应,并讨论了支持其使用的主要证据。我们的讨论重点是L-苯丙氨酸、白藓、凯林、银杏,以及维生素和矿物质,包括维生素B12、C和E、叶酸和锌,它们被用作单一疗法或与其他治疗方法联合用于白癜风的治疗。

相似文献

1
Alternative Systemic Treatments for Vitiligo: A Review.白癜风的替代全身治疗:综述
Am J Clin Dermatol. 2015 Dec;16(6):463-74. doi: 10.1007/s40257-015-0153-5.
2
Treatment of vitiligo vulgaris with narrow-band UVB and oral Polypodium leucotomos extract: a randomized double-blind placebo-controlled study.窄谱中波紫外线联合口服白藓皮提取物治疗寻常型白癜风:一项随机双盲安慰剂对照研究。
J Eur Acad Dermatol Venereol. 2007 Aug;21(7):942-50. doi: 10.1111/j.1468-3083.2006.02132.x.
3
A Systematic Review of Nutrition, Supplement, and Herbal-Based Adjunctive Therapies for Vitiligo.一项针对营养、补充剂和草药辅助疗法治疗白癜风的系统评价。
J Altern Complement Med. 2021 Apr;27(4):294-311. doi: 10.1089/acm.2020.0292. Epub 2020 Dec 18.
4
Treatment of vitiligo vulgaris with narrow band UVB (311 nm) for one year and the effect of addition of folic acid and vitamin B12.用窄谱中波紫外线(311nm)治疗寻常型白癜风一年及添加叶酸和维生素B12的效果
Acta Derm Venereol. 2002;82(5):369-72. doi: 10.1080/000155502320624113.
5
Treatment of vitiligo with broadband ultraviolet B and vitamins.采用宽带紫外线B和维生素治疗白癜风。
Int J Dermatol. 2006 Jan;45(1):63-5. doi: 10.1111/j.1365-4632.2005.02447.x.
6
A systematic review of natural health product treatment for vitiligo.一项关于白癜风天然健康产品治疗的系统评价。
BMC Dermatol. 2008 May 22;8:2. doi: 10.1186/1471-5945-8-2.
7
Functional nutrition as integrated approach in vitiligo management.功能性营养作为白癜风管理的综合方法。
Dermatol Ther. 2019 Jul;32(4):e12625. doi: 10.1111/dth.12625. Epub 2018 Aug 28.
8
The Role of Diet and Supplements in Vitiligo Management.饮食与补充剂在白癜风治疗中的作用
Dermatol Clin. 2017 Apr;35(2):235-243. doi: 10.1016/j.det.2016.11.012.
9
Therapeutic interventions for vitiligo.白癜风的治疗干预措施。
J Am Acad Dermatol. 2008 Oct;59(4):713-7. doi: 10.1016/j.jaad.2008.06.023.
10
A case study to evaluate the treatment of vitiligo with khellin encapsulated in L-phenylalanin stabilized phosphatidylcholine liposomes in combination with ultraviolet light therapy.一项评估包裹于L-苯丙氨酸稳定化磷脂酰胆碱脂质体中的凯林联合紫外线疗法治疗白癜风的病例研究。
Eur J Dermatol. 2003 Sep-Oct;13(5):474-7.

引用本文的文献

1
Diet in Dermatology: Review of Diet's Influence on the Conditions of Rosacea, Hidradenitis Suppurativa, Herpes Labialis, and Vitiligo.皮肤病学中的饮食:饮食对酒渣鼻、化脓性汗腺炎、唇疱疹和白癜风病情影响的综述
Am J Lifestyle Med. 2021 Jul 2;17(1):152-160. doi: 10.1177/15598276211026592. eCollection 2023 Jan-Feb.
2
Topological Indices of Novel Drugs Used in Autoimmune Disease Vitiligo Treatment and Its QSPR Modeling.用于治疗自身免疫性疾病白癜风的新型药物的拓扑指数及其 QSPR 建模。
Biomed Res Int. 2022 Nov 15;2022:6045066. doi: 10.1155/2022/6045066. eCollection 2022.
3
Serum Zinc and Inflammatory Cytokines in Vitiligo.
白癜风患者血清锌与炎性细胞因子
J Clin Aesthet Dermatol. 2020 Dec;13(12 Suppl 1):S29-S33. Epub 2020 Dec 1.
4
Phytochemical and Nutritional Quality Changes During Irrigation and Postharvest Processing of the Underutilized Vegetable African Nightshade.未充分利用的蔬菜非洲茄在灌溉及采后加工过程中的植物化学和营养品质变化
Front Nutr. 2020 Nov 16;7:576532. doi: 10.3389/fnut.2020.576532. eCollection 2020.
5
Overexpression of improved EPSPS gene results in field level glyphosate tolerance and higher grain yield in rice.过表达改良的 EPSPS 基因导致水稻田间水平的草甘膦耐受性和更高的籽粒产量。
Plant Biotechnol J. 2020 Dec;18(12):2504-2519. doi: 10.1111/pbi.13428. Epub 2020 Jul 24.
6
Are Patients with Vitiligo More Prone to Myocardial Infarction?: A Case-control Study.白癜风患者更容易患心肌梗死吗?一项病例对照研究。
J Clin Aesthet Dermatol. 2019 Nov;12(11):28-31. Epub 2019 Nov 1.
7
Home phototherapy for patients with vitiligo: challenges and solutions.白癜风患者的家庭光疗:挑战与解决方案
Clin Cosmet Investig Dermatol. 2019 Jun 28;12:451-459. doi: 10.2147/CCID.S185798. eCollection 2019.
8
Serum Zinc Level in Vitiligo: A Case-control Study.白癜风患者血清锌水平:一项病例对照研究。
Indian J Dermatol. 2018 May-Jun;63(3):227-230. doi: 10.4103/ijd.IJD_457_16.
9
Herbal Compounds for the Treatment of Vitiligo: A Review.用于治疗白癜风的草药化合物:综述
Open Access Maced J Med Sci. 2018 Jan 21;6(1):203-207. doi: 10.3889/oamjms.2018.048. eCollection 2018 Jan 25.
10
[Systemic treatment of vitiligo : Balance and current developments].[白癜风的系统治疗:现状与新进展]
Hautarzt. 2017 Nov;68(11):876-884. doi: 10.1007/s00105-017-4065-6.