Grimes Pearl E, Nashawati Rama
Division of Dermatology, Vitiligo & Pigmentation Institute of Southern California, David Geffen School of Medicine, University of California, Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA; Vitiligo & Pigmentation Institute of Southern California, 5670 Wilshire Boulevard, #650, Los Angeles, CA 90036, USA.
Vitiligo & Pigmentation Institute of Southern California, 5670 Wilshire Boulevard, #650, Los Angeles, CA 90036, USA.
Dermatol Clin. 2017 Apr;35(2):235-243. doi: 10.1016/j.det.2016.11.012.
Vitiligo is an autoimmune disorder that involves the interplay between oxidative stress and the immune system. Preliminary observations suggest that the presence of gluten in the diet may play a role in vitiligo development in some patients, but to date vitiligo-specific diets have not been studied. The role of oral supplements, including vitamins, minerals, and botanicals, is increasingly being investigated as adjuncts to conventional medical treatment due to their antioxidant and immunomodulatory activity. Studies suggest that many of these agents may have some efficacy as monotherapy, but more often as adjuncts to topical agents and phototherapy.
白癜风是一种自身免疫性疾病，涉及氧化应激与免疫系统之间的相互作用。初步观察表明，饮食中麸质的存在可能在某些患者白癜风的发展中起作用，但迄今为止，尚未对白癜风特异性饮食进行研究。由于其抗氧化和免疫调节活性，包括维生素、矿物质和植物药在内的口服补充剂作为传统医学治疗辅助手段的作用正越来越受到研究。研究表明，这些药物中的许多作为单一疗法可能有一定疗效，但更多时候是作为局部用药和光疗的辅助手段。
