Choudhury A R, Mukherjee M, Sharma A, Talukder G, Ghosh P K
Indian J Pediatr. 1989 Jul-Aug;56(4):493-9. doi: 10.1007/BF02722422.
Retrospective study was carried out in 1,15,851 consecutive births in five hospitals, and prospective study of 10,415 consecutive births in one hospital of West Bengal. The overall frequency of congenital defects was 4.42/1000 live births. Incidence of NTD and talipes was predominant in rainy season, whereas cleft palate with/without hare lip had highest frequency during winter. Incidence of these anomalies decreased with increasing birth order. The frequency was noted to decline with increasing maternal age, 21-25 years age group had maximum number of malformed babies. Sex ratio and religion, however, did not have any correlation with the incidence of these malformations. When comparison was done between urban and rural population no statistically significant variation was observed.
对五家医院连续出生的115851例婴儿进行了回顾性研究，并对西孟加拉邦一家医院连续出生的10415例婴儿进行了前瞻性研究。先天性缺陷的总体发生率为4.42/1000活产。神经管缺陷和畸形足的发生率在雨季占主导地位，而伴有或不伴有唇裂的腭裂在冬季发生率最高。这些异常的发生率随着出生顺序的增加而降低。随着母亲年龄的增加，发生率呈下降趋势，21 - 25岁年龄组的畸形婴儿数量最多。然而，性别比例和宗教与这些畸形的发生率没有任何关联。在城乡人口之间进行比较时，未观察到统计学上的显著差异。
