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在显微镜下:从病原体到益生菌,再回归本源。

Under the microscope: From pathogens to probiotics and back.

作者信息

Sleator Roy D

机构信息

a Department of Biological Sciences ; Cork Institute of Technology ; Bishopstown , Cork , Ireland.

出版信息

Bioengineered. 2015;6(5):275-82. doi: 10.1080/21655979.2015.1089368.

Abstract

The review centers on the human gastrointestinal tract; focusing first on the bacterial stress responses needed to overcome the physiochemical defenses of the host, specifically how these stress survival strategies can be used as targets for alternative infection control strategies. The concluding section focuses on recent developments in molecular diagnostics; centring on the shifting paradigm from culture to molecular based diagnostics.

摘要

该综述聚焦于人类胃肠道;首先关注克服宿主物理化学防御所需的细菌应激反应,特别是这些应激生存策略如何可被用作替代感染控制策略的靶点。结论部分聚焦于分子诊断的最新进展;以从培养到基于分子的诊断这一转变的范式为中心。

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