中国乙型肝炎病毒感染的流行病学：现状与挑战。
Epidemiology of Hepatitis B Virus Infection in China: Current Status and Challenges.
机构信息
Department of Epidemiology, and the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Fourth Military Medical University, Xi'an, Shaanxi, China.
出版信息
J Clin Transl Hepatol. 2014 Mar;2(1):15-22. doi: 10.14218/JCTH.2013.00030. Epub 2014 Mar 15.
Abstract
The prevalence of hepatitis B is high in China. Based on the National Disease Supervision Information Management System of China, the mean reported incidence of hepatitis B was 84.3 per 100,000 in China between 2005 and 2010. There are differences in population distribution based on region and ethnic group. Here, risk factors, virological characteristics, and prophylaxis of hepatitis B in China are reviewed. Although the prevalence of HBV infection is gradually declining, there are many challenges in HBV infection control, including higher prevalence in floating population, poor compliance of antiviral therapy, and high disease burden.
摘要
乙型肝炎在中国的流行率很高。根据中国国家疾病监测信息管理系统的数据，2005 年至 2010 年期间，中国乙型肝炎的平均报告发病率为每 10 万人 84.3 例。人群分布存在地区和民族差异。本文就中国乙型肝炎的危险因素、病毒学特征和预防进行综述。虽然 HBV 感染的流行率正在逐渐下降，但 HBV 感染控制仍面临诸多挑战，包括流动人口感染率较高、抗病毒治疗依从性差以及疾病负担较重等。
相似文献
1
Epidemiology of Hepatitis B Virus Infection in China: Current Status and Challenges.
J Clin Transl Hepatol. 2014 Mar;2(1):15-22. doi: 10.14218/JCTH.2013.00030. Epub 2014 Mar 15.
2
Hepatitis B infection in the general population of China: a systematic review and meta-analysis.
BMC Infect Dis. 2019 Sep 18;19(1):811. doi: 10.1186/s12879-019-4428-y.
3
Hepatitis B virus infection in hilly/mountainous regions of southeastern China: a locality-dependent epidemiology.
BMC Infect Dis. 2017 Dec 29;17(1):809. doi: 10.1186/s12879-017-2922-7.
4
China's efforts to shed its title of "Leader in liver disease".
Drug Discov Ther. 2007 Oct;1(2):84-5.
5
A case-control study of hepatitis B and C virus infection as risk factors for hepatocellular carcinoma in Henan, China.
Int J Epidemiol. 1998 Aug;27(4):574-8. doi: 10.1093/ije/27.4.574.
6
Safety of hepatitis B virus core antibody-positive grafts in liver transplantation: A single-center experience in China.
World J Gastroenterol. 2018 Dec 28;24(48):5525-5536. doi: 10.3748/wjg.v24.i48.5525.
7
Epidemiology and prevention of hepatitis B virus infection in China.
J Viral Hepat. 2010 Mar;17 Suppl 1:4-9. doi: 10.1111/j.1365-2893.2010.01266.x.
8
Seroepidemiology of hepatitis B virus infection in 2 million men aged 21-49 years in rural China: a population-based, cross-sectional study.
Lancet Infect Dis. 2016 Jan;16(1):80-86. doi: 10.1016/S1473-3099(15)00218-2. Epub 2015 Aug 9.
9
Update on epidemiology of hepatitis B and C in China.
J Gastroenterol Hepatol. 2013 Aug;28 Suppl 1:7-10. doi: 10.1111/jgh.12220.
10
Assessment of the duplicate notifiable reporting of hepatitis B infection in Zhejiang province, China, 2005-2015.
Vaccine. 2017 Aug 24;35(36):4702-4706. doi: 10.1016/j.vaccine.2017.07.039. Epub 2017 Jul 24.
引用本文的文献
1
Tenofovir alafenamide is superior to tenofovir disoproxil fumarate and entecavir in cost-effectiveness of treatment of chronic hepatitis B in china with new volume-based procurement policy.
PLoS One. 2025 Jul 11;20(7):e0327298. doi: 10.1371/journal.pone.0327298. eCollection 2025.
2
Geographic diversity of human liver cancers mirrors global social inequalities.
Front Oncol. 2025 May 16;15:1565692. doi: 10.3389/fonc.2025.1565692. eCollection 2025.
3
Phylodynamics of hepatitis B virus genotype B in East Asia: A population genomics analysis.
J Biol Methods. 2025 Jan 17;12(1):e99010048. doi: 10.14440/jbm.2025.0084. eCollection 2025.
4
Decreasing hepatitis B seroprevalence in pregnant women in Taiwan between 2016 and 2021: a claim-based cohort study.
BMC Public Health. 2025 Jan 9;25(1):111. doi: 10.1186/s12889-025-21308-3.
5
Liver Cancer Mortality Disparities at a Fine Scale Among Subpopulations in China: Nationwide Analysis of Spatial and Temporal Trends.
JMIR Public Health Surveill. 2024 Aug 8;10:e54967. doi: 10.2196/54967.
6
The hepatocellular carcinoma risk in patients with HBV-related cirrhosis: a competing risk nomogram based on a 4-year retrospective cohort study.
Front Oncol. 2024 May 16;14:1398968. doi: 10.3389/fonc.2024.1398968. eCollection 2024.
7
Cancer literacy differences of basic knowledge, prevention, early detection, treatment and recovery: a cross-sectional study of urban and rural residents in Northeast China.
Front Public Health. 2024 May 14;12:1367947. doi: 10.3389/fpubh.2024.1367947. eCollection 2024.
8
Trends in Mortality of Cirrhosis in China: An Analysis of the China Death Surveillance Database from 2008 to 2020.
J Clin Transl Hepatol. 2024 Mar 28;12(3):236-244. doi: 10.14218/JCTH.2023.00454. Epub 2024 Jan 22.
9
A Narrative Review on the Specific Pattern of HBV Genotype in Bangladesh: Clinical Implications for Management.
Euroasian J Hepatogastroenterol. 2023 Jul-Dec;13(2):152-158. doi: 10.5005/jp-journals-10018-1412.
10
IL2-inducible T-cell Kinase is Required for HBV-induced Type T Interferon Expression and Antiviral Response.
J Clin Transl Hepatol. 2023 Aug 28;11(4):918-924. doi: 10.14218/JCTH.2022.00299. Epub 2023 Feb 7.
本文引用的文献
1
Risk of vertical transmission of hepatitis B after amniocentesis in HBs antigen-positive mothers.
J Hepatol. 2014 Mar;60(3):523-9. doi: 10.1016/j.jhep.2013.11.008. Epub 2013 Nov 19.
2
New loci associated with chronic hepatitis B virus infection in Han Chinese.
Nat Genet. 2013 Dec;45(12):1499-503. doi: 10.1038/ng.2809. Epub 2013 Oct 27.
3
A novel B/C inter-genotype recombinant of hepatitis B virus identified in north-west China.
J Gen Virol. 2014 Jan;95(Pt 1):153-155. doi: 10.1099/vir.0.054023-0. Epub 2013 Oct 15.
4
Occult hepatitis B virus infection in anti-HBs-positive infants born to HBsAg-positive mothers in China.
PLoS One. 2013 Aug 12;8(8):e70768. doi: 10.1371/journal.pone.0070768. eCollection 2013.
5
Reprint of: Epidemiological serosurvey of Hepatitis B in China--declining HBV prevalence due to Hepatitis B vaccination.
Vaccine. 2013 Dec 27;31 Suppl 9:J21-8. doi: 10.1016/j.vaccine.2013.08.012. Epub 2013 Aug 12.
6
A complete genomic analysis of hepatitis B virus isolated from 516 Chinese patients with different clinical manifestations.
J Med Virol. 2013 Oct;85(10):1698-704. doi: 10.1002/jmv.23640. Epub 2013 Jul 12.
7
[Economic burden and related factors on inpatients with HBV-related diseases in Shandong province].
Zhonghua Liu Xing Bing Xue Za Zhi. 2013 Mar;34(3):267-72.
8
[Prevalence of occult hepatitis B virus infection and its phylogenetic features among mother-teenager pairs].
Zhonghua Liu Xing Bing Xue Za Zhi. 2013 Mar;34(3):210-3.
9
Prevalence and risk factors of hepatitis C and B virus infections in hemodialysis patients and their spouses: a multicenter study in Beijing, China.
J Med Virol. 2013 Mar;85(3):425-32. doi: 10.1002/jmv.23486.
10
Occult HBV infection.
Semin Immunopathol. 2013 Jan;35(1):39-52. doi: 10.1007/s00281-012-0327-7. Epub 2012 Jul 26.
Zotero 插件