一种基于葡萄糖氧化酶催化金纳米颗粒放大的用于葡萄糖检测的高通量比色测定法。
A high-throughput colorimetric assay for glucose detection based on glucose oxidase-catalyzed enlargement of gold nanoparticles.
作者信息
Xiong Yanmei, Zhang Yuyan, Rong Pengfei, Yang Jie, Wang Wei, Liu Dingbin
机构信息
College of Chemistry, Research Center for Analytical Sciences, State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Molecular Recognition and Biosensing, and Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, 94 Weijin Road, Tianjin 300071, China.
出版信息
Nanoscale. 2015 Oct 14;7(38):15584-8. doi: 10.1039/c5nr03758a. Epub 2015 Sep 11.
We developed a simple high-throughput colorimetric assay to detect glucose based on the glucose oxidase (GOx)-catalysed enlargement of gold nanoparticles (AuNPs). Compared with the currently available glucose kit method, the AuNP-based assay provides higher clinical sensitivity at lower cost, indicating its great potential to be a powerful tool for clinical screening of glucose.
我们开发了一种基于葡萄糖氧化酶（GOx）催化金纳米颗粒（AuNPs）增大来检测葡萄糖的简单高通量比色法。与目前可用的葡萄糖试剂盒方法相比，基于金纳米颗粒的检测方法以更低的成本提供了更高的临床灵敏度，表明其极有可能成为葡萄糖临床筛查的有力工具。
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