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反向性痤疮:诊断与治疗中的难点

Acne inversa: difficulties in diagnostics and therapy.

作者信息

Bergler-Czop Beata, Hadasik Karolina, Brzezińska-Wcisło Ligia

机构信息

Department of Dermatology, Silesian Medical University, Katowice, Poland. Head of the Department: Prof. Ligia Brzezińska-Wcisło MD, PhD.

出版信息

Postepy Dermatol Alergol. 2015 Aug;32(4):296-301. doi: 10.5114/pdia.2014.44012. Epub 2015 Aug 12.

Abstract

Acne inversa (hidradenitis suppurativa) is a potentially severe and chronic inflammatory disease with a significant negative influence on the quality of life. Usually, lesions are located in the areas of skin folds and it is characterized by the presence of painful nodules and fistulas with a tendency to tissue fibrosis. Currently, it is suggested that follicular occlusion by infundibular hyperkeratosis plays a crucial role in pathogenesis and an occupation of apocrine sweat glands is a secondary phenomenon. Most often, it refers to men after puberty. This article tries to present the latest theory concerning the etiology of inverted acne and methods of its treatment. It also describes the most common errors in diagnostic and therapeutic procedures, which are mainly connected with repeated and long antibiotic therapy and not radical surgical treatment.

摘要

化脓性汗腺炎是一种潜在的严重慢性炎症性疾病,对生活质量有重大负面影响。通常,病变位于皮肤褶皱部位,其特征是存在疼痛性结节和瘘管,并伴有组织纤维化倾向。目前认为,漏斗部角化过度导致的毛囊阻塞在发病机制中起关键作用,顶泌汗腺受累是继发现象。此病最常发生于青春期后的男性。本文旨在介绍有关化脓性汗腺炎病因的最新理论及其治疗方法。文中还描述了诊断和治疗过程中最常见的错误,这些错误主要与反复长期使用抗生素治疗以及手术治疗不彻底有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a93f/4565831/f9a531dd4622/PDIA-32-23146-g001.jpg

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