Department of Microbial Diseases, UCL Eastman Dental Institute, London, UK.
J Appl Oral Sci. 2010 Sep-Oct;18(5):498-502. doi: 10.1590/s1678-77572010000500012.
Ideally root canal irrigants should have, amongst other properties, antimicrobial action associated with a lack of toxicity against periapical tissues. Sodium hypochlorite (NaOCl) is a widely used root canal irrigant, however it has been shown to have a cytotoxic effect on vital tissue and therefore it is prudent to investigate alternative irrigants. Sterilox's Aquatine Alpha Electrolyte® belongs to the group of the super-oxidized waters; it consists of a mixture of oxidizing substances, and has been suggested to be used as root canal irrigant. Super-oxidized waters have been shown to provide efficient cleaning of root canal walls, and have been proposed to be used for the disinfection of medical equipment.
To compare the antimicrobial action against Enterococcus faecalis of NaOCl, Optident Sterilox Electrolyte Solution® and Sterilox's Aquatine Alpha Electrolyte® when used as irrigating solutions in a bovine root canal model.
Root sections were prepared and inoculated with E. faecalis JH2-2. After 10 days of incubation the root canals were irrigated using one of three solutions (NaOCl, Optident Sterilox Electrolyte Solution®and Sterilox's Aquatine Alpha Electrolyte®) and subsequently sampled by grinding dentin using drills. The debris was placed in BHI broth and dilutions were plated onto fresh agar plates to quantify growth.
Sodium hypochlorite was the only irrigant to eliminate all bacteria. When the dilutions were made, although NaOCl was still statistically superior, Sterilox's Aquatine Alpha Electrolyte® solution was superior to Optident Sterilox Electrolyte Solution®.
Under the conditions of this study Sterilox's Aquatine Alpha Electrolyte® appeared to have significantly more antimicrobial action compared to the Optident Sterilox Electrolyte Solution® alone, however NaOCl was the only solution able to consistently eradicate E. faecalis in the model.
理想情况下，根管冲洗剂除了具有其他特性外，还应具有抗微生物作用，并且对根尖组织无毒。次氯酸钠（NaOCl）是一种广泛使用的根管冲洗剂，但已显示出对活组织有细胞毒性作用，因此明智的做法是研究替代冲洗剂。Sterilox 的 Aquatine Alpha Electrolyte®属于超氧化水组；它由氧化物质的混合物组成，并且已被建议用作根管冲洗剂。超氧化水已被证明可以有效地清洁根管壁，并被提议用于医疗设备的消毒。
比较在牛根管模型中用作冲洗液时，次氯酸钠、Optident Sterilox 电解质溶液®和 Sterilox 的 Aquatine Alpha Electrolyte®对粪肠球菌的抗菌作用。
制备根段并接种粪肠球菌 JH2-2。孵育 10 天后，用三种溶液中的一种（次氯酸钠、Optident Sterilox 电解质溶液®和 Sterilox 的 Aquatine Alpha Electrolyte®）冲洗根管，然后用钻头研磨牙本质取样。将碎片放入 BHI 肉汤中，并将稀释液涂在新鲜琼脂平板上以定量生长。
只有次氯酸钠才能消除所有细菌。尽管次氯酸钠仍然具有统计学优势，但当进行稀释时，Sterilox 的 Aquatine Alpha Electrolyte®溶液优于 Optident Sterilox Electrolyte Solution®。
在本研究的条件下，与单独使用 Optident Sterilox Electrolyte Solution®相比，Sterilox 的 Aquatine Alpha Electrolyte®似乎具有更强的抗菌作用，但是只有次氯酸钠才能在该模型中持续消除粪肠球菌。
