山楂（山楂亚种单性山楂Jacq.）的一些生物活性化合物及抗氧化特性研究
The investigation of some bioactive compounds and antioxidant properties of hawthorn (Crataegus monogyna subsp. monogyna Jacq).
作者信息
Keser Serhat, Celik Sait, Turkoglu Semra, Yilmaz Ökkes, Turkoglu Ismail
机构信息
Department of Chemistry, Faculty of Science, Firat University, Elazig, Turkey.
Department of Chemistry, Faculty of Science and Arts, Usak University, Usak, Turkey.
出版信息
J Intercult Ethnopharmacol. 2014 Apr-Jun;3(2):51-5. doi: 10.5455/jice.20140120103320. Epub 2014 May 23.
AIM
The antioxidant and pharmacological effects of hawthorn have mainly been attributed to the polyphenolic contents. The aim of this research is to determine some bioactive compounds and antioxidant properties of hawthorn aqueous and ethanol extracts of leaves, flowers, and ripened fruits.
MATERIALS AND METHODS
For this purpose, antioxidant activities of extracts were assessed on DPPH•, ABTS•+, superoxide scavenging, reducing power and ferrous metal chelating activity assays and phenolic content of extracts was determined by Folin-Cioacalteu's reagent.
RESULTS
The flavonoids including rutin, apigenin, myricetin, quercetin, naringenin and kaempferol, were identified by high-performance liquid chromatography in the hawthorn extract.
CONCLUSION
It was observed the aqueous and ethanol extracts of Crataegus monogyna subsp. monogyna fruits showed the highest activity in reducing power and metal chelating activity assays. In addition, it was determined that the aqueous flower extract showed higher flavonoid content than aqueous leaves extract. The antioxidant and pharmacological effects of hawthorn have mainly been attributed to the polyphenolic contents.
目的
山楂的抗氧化和药理作用主要归因于其多酚类成分。本研究的目的是确定山楂叶、花和成熟果实的水提取物和乙醇提取物中的一些生物活性化合物及其抗氧化特性。
材料与方法
为此，通过DPPH•、ABTS•+、超氧化物清除、还原能力和亚铁离子螯合活性测定来评估提取物的抗氧化活性，并使用福林-酚试剂测定提取物中的酚含量。
结果
通过高效液相色谱法在山楂提取物中鉴定出了包括芦丁、芹菜素、杨梅素、槲皮素、柚皮苷和山奈酚在内的黄酮类化合物。
结论
观察到单瓣山楂亚种单瓣山楂果实的水提取物和乙醇提取物在还原能力和金属螯合活性测定中表现出最高活性。此外，还确定花的水提取物比叶的水提取物具有更高的黄酮类含量。山楂的抗氧化和药理作用主要归因于其多酚类成分。
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