• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Preparing for an Aging World: Engaging Biogerontologists, Geriatricians, and the Society.为老龄化世界做准备:让生物老年医学专家、老年病学家及社会参与进来。
J Gerontol A Biol Sci Med Sci. 2016 Apr;71(4):435-44. doi: 10.1093/gerona/glv164. Epub 2015 Sep 29.
2
Can biogerontologists and geriatricians unite to apply aging science to health care in the decade ahead?生物老年学家和老年医学专家能否联合起来,将衰老科学应用于未来十年的医疗保健?
J Gerontol A Biol Sci Med Sci. 2010 Nov;65(11):1193-7. doi: 10.1093/gerona/glq117. Epub 2010 Jun 30.
3
Japan as the front-runner of super-aged societies: Perspectives from medicine and medical care in Japan.日本作为超老龄化社会的领跑者:来自日本医学与医疗护理的视角
Geriatr Gerontol Int. 2015 Jun;15(6):673-87. doi: 10.1111/ggi.12450. Epub 2015 Feb 5.
4
Geriatrics for the 3rd millennium.第三个千年的老年医学。
Wien Klin Wochenschr. 2000 May 5;112(9):386-93.
5
Successful aging. How increased life expectancy and medical advances are changing geriatric care.成功老龄化。预期寿命的增加和医学进步如何改变老年护理。
Geriatrics. 2001 Jan;56(1):35-9; quiz 40.
6
Translational geroscience: emphasizing function to achieve optimal longevity.转化老年科学:强调功能以实现最佳长寿。
Aging (Albany NY). 2014 Sep;6(9):718-30. doi: 10.18632/aging.100694.
7
Aging: the triumph of humanity-are we prepared to face the challenge?衰老:人类的胜利——我们是否准备好迎接挑战?
Indian J Public Health. 2012 Jul-Sep;56(3):189-95. doi: 10.4103/0019-557X.104217.
8
Implementation of longevity-promoting supplements and medications in public health practice: achievements, challenges and future perspectives.在公共卫生实践中推广延寿补充剂和药物的实施:成就、挑战和未来展望。
J Transl Med. 2017 Jul 20;15(1):160. doi: 10.1186/s12967-017-1259-8.
9
Caring for older Americans: the future of geriatric medicine.关爱美国老年人:老年医学的未来。
J Am Geriatr Soc. 2005 Jun;53(6 Suppl):S245-56. doi: 10.1111/j.1532-5415.2005.53350.x.
10
Research gaps in the demography of aging with disability.老龄化与残疾人口统计学研究中的空白
Disabil Health J. 2014 Jan;7(1 Suppl):S60-3. doi: 10.1016/j.dhjo.2013.04.009.

引用本文的文献

1
Immunotherapeutic targeting of aging-associated isoDGR motif in chronic lung inflammation.慢性肺部炎症中衰老相关异天冬酰胺-甘氨酸-精氨酸基序的免疫治疗靶向作用
Aging Cell. 2025 Apr;24(4):e14425. doi: 10.1111/acel.14425. Epub 2025 Jan 5.
2
Strength gains after 12 weeks of resistance training correlate with neurochemical markers of brain health in older adults: a randomized control H-MRS study.抗阻训练 12 周后的力量增益与老年人的大脑健康神经化学标志物相关:一项随机对照 H-MRS 研究。
Geroscience. 2023 Jun;45(3):1837-1855. doi: 10.1007/s11357-023-00732-6. Epub 2023 Jan 26.
3
Aging and immunotherapies: New horizons for the golden ages.衰老与免疫疗法:黄金时代的新视野。
Aging Cancer. 2020 Dec;1(1-4):30-44. doi: 10.1002/aac2.12014. Epub 2020 Sep 30.
4
Molecular Mechanisms of Exercise and Healthspan.运动与健康寿命的分子机制。
Cells. 2022 Mar 3;11(5):872. doi: 10.3390/cells11050872.
5
Cross-cultural adaptation and validation of the caregiver contribution to self-care of chronic illness inventory in China: a cross-sectional study.中文版慢性病患者自我护理贡献量表的跨文化调适与验证:一项横断面研究。
BMJ Open. 2021 Sep 7;11(9):e048875. doi: 10.1136/bmjopen-2021-048875.
6
Prevalence and the factors associated with malnutrition risk in elderly Chinese inpatients.中国老年住院患者营养不良风险的患病率及其相关因素。
Aging Med (Milton). 2021 Feb 17;4(2):120-127. doi: 10.1002/agm2.12143. eCollection 2021 Jun.
7
Metabolic View on Human Healthspan: A Lipidome-Wide Association Study.人类健康寿命的代谢视角:一项全脂质组关联研究。
Metabolites. 2021 Apr 30;11(5):287. doi: 10.3390/metabo11050287.
8
Identification of comprehensive geriatric assessment-based risk factors for insomnia in elderly Chinese hospitalized patients.识别中国老年住院患者中基于综合老年评估的失眠风险因素。
Aging Med (Milton). 2021 Feb 4;4(1):26-34. doi: 10.1002/agm2.12146. eCollection 2021 Mar.
9
lifespan measurement.寿命测量
Transl Med Aging. 2020;4:1-10. Epub 2019 Dec 7.
10
Insulin-like Growth Factor-1 and IGF Binding Proteins Predict All-Cause Mortality and Morbidity in Older Adults.胰岛素样生长因子-1 和 IGF 结合蛋白可预测老年人的全因死亡率和发病率。
Cells. 2020 Jun 1;9(6):1368. doi: 10.3390/cells9061368.

本文引用的文献

1
Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms.延长寿命的热量限制或mTOR抑制通过不同机制损害老年小鼠的适应性免疫。
Aging Cell. 2015 Feb;14(1):130-8. doi: 10.1111/acel.12280. Epub 2014 Nov 26.
2
Geroscience: linking aging to chronic disease.衰老学:将衰老与慢性疾病联系起来。
Cell. 2014 Nov 6;159(4):709-13. doi: 10.1016/j.cell.2014.10.039.
3
Better access, quality, and cost for clinically complex veterans with home-based primary care.为患有临床复杂疾病的退伍军人提供更好的家庭初级保健服务,包括更好的可及性、质量和成本效益。
J Am Geriatr Soc. 2014 Oct;62(10):1954-61. doi: 10.1111/jgs.13030.
4
Translational geroscience: emphasizing function to achieve optimal longevity.转化老年科学:强调功能以实现最佳长寿。
Aging (Albany NY). 2014 Sep;6(9):718-30. doi: 10.18632/aging.100694.
5
Mechanistic target of rapamycin (mTOR): a point of convergence in the action of insulin/IGF-1 and G protein-coupled receptor agonists in pancreatic cancer cells.雷帕霉素靶蛋白(mTOR):胰岛素/IGF-1 和 G 蛋白偶联受体激动剂在胰腺癌细胞中作用的交汇点。
Front Physiol. 2014 Sep 23;5:357. doi: 10.3389/fphys.2014.00357. eCollection 2014.
6
Comprehensive longitudinal health care in the home for high-cost beneficiaries: a critical strategy for population health management.为高成本受益人群提供全面的家庭纵向医疗保健:人口健康管理的关键策略。
J Am Geriatr Soc. 2014 Oct;62(10):1974-6. doi: 10.1111/jgs.13049. Epub 2014 Oct 7.
7
Aging research-where do we stand and where are we going?衰老研究——我们处于什么位置,又将走向何方?
Cell. 2014 Sep 25;159(1):15-19. doi: 10.1016/j.cell.2014.08.041.
8
Effects of home-based primary care on Medicare costs in high-risk elders.居家初级保健对高危老年人医疗保险费用的影响。
J Am Geriatr Soc. 2014 Oct;62(10):1825-31. doi: 10.1111/jgs.12974. Epub 2014 Jul 18.
9
Immune memory-boosting dose of rapamycin impairs macrophage vesicle acidification and curtails glycolysis in effector CD8 cells, impairing defense against acute infections.雷帕霉素增强免疫记忆的剂量会损害巨噬细胞囊泡酸化,并抑制效应CD8细胞中的糖酵解,从而削弱对急性感染的防御能力。
J Immunol. 2014 Jul 15;193(2):757-63. doi: 10.4049/jimmunol.1400188. Epub 2014 Jun 9.
10
Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases.慢性炎症(炎症衰老)及其对与年龄相关疾病的潜在贡献。
J Gerontol A Biol Sci Med Sci. 2014 Jun;69 Suppl 1:S4-9. doi: 10.1093/gerona/glu057.

为老龄化世界做准备:让生物老年医学专家、老年病学家及社会参与进来。

Preparing for an Aging World: Engaging Biogerontologists, Geriatricians, and the Society.

作者信息

Nikolich-Žugich Janko, Goldman Dana P, Cohen Paul R, Cortese Denis, Fontana Luigi, Kennedy Brian K, Mohler M Jane, Olshansky S Jay, Perls Thomas, Perry Daniel, Richardson Arlan, Ritchie Christine, Wertheimer Anne M, Faragher Richard G A, Fain Mindy J

机构信息

Arizona Center on Aging, Department of Immunobiology, and Department of Medicine, University of Arizona College of Medicine, Tucson. Schaeffer Center for Health Policy and Economics, University of Southern California, Los Angeles. School of Information, University of Arizona College of Science, Tucson.

Schaeffer Center for Health Policy and Economics, University of Southern California, Los Angeles.

出版信息

J Gerontol A Biol Sci Med Sci. 2016 Apr;71(4):435-44. doi: 10.1093/gerona/glv164. Epub 2015 Sep 29.

DOI:10.1093/gerona/glv164
PMID:26419976
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5014189/
Abstract

Although the demographic revolution has produced hundreds of millions people aged 65 and older, a substantial segment of that population is not enjoying the benefits of extended healthspan. Many live with multiple chronic conditions and disabilities that erode the quality of life. The consequences are also costly for society. In the United States, the most costly 5% of Medicare beneficiaries account for approximately 50% of Medicare's expenditures. This perspective summarizes a recent workshop on biomedical approaches to best extend healthspan as way to reduce age-related dysfunction and disability. We further specify the action items necessary to unite health professionals, scientists, and the society to partner around the exciting and palpable opportunities to extend healthspan.

摘要

尽管人口结构变革造就了数亿65岁及以上的老年人,但这一群体中的很大一部分并未享受到健康寿命延长带来的益处。许多人患有多种慢性疾病和残疾,生活质量因此受到影响。这对社会而言成本也很高。在美国,医保支出最高的5%的医保受益人约占医保总支出的50%。本观点总结了近期一场关于生物医学方法的研讨会,该方法旨在最大程度地延长健康寿命,以此减少与年龄相关的机能障碍和残疾。我们进一步明确了必要的行动事项,以便团结医疗专业人员、科学家和社会各界,围绕延长健康寿命这一令人兴奋且切实可行的机遇展开合作。