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富血小板血浆治疗雄激素性脱发的疗效

Efficacy of platelet-rich plasma in treatment of androgenic alopecia.

作者信息

Singhal Parul, Agarwal Sachin, Dhot Paramjeet Singh, Sayal Satish K

机构信息

Department of Pathology, Santosh Medical College, Ghaziabad, Uttar Pradesh, India.

Department of Dermatology, Santosh Medical College, Ghaziabad, Uttar Pradesh, India.

出版信息

Asian J Transfus Sci. 2015 Jul-Dec;9(2):159-62. doi: 10.4103/0973-6247.162713.

DOI:10.4103/0973-6247.162713
PMID:26420936
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4562137/
Abstract

BACKGROUND

Platelet-rich plasma (PRP) has shown remarkable beneficial effects without any major adverse reactions in the treatment of androgenic alopecia. The growth factors in activated autologous PRP induce the proliferation of dermal papilla cells.

OBJECTIVES

The objective was to investigate the clinical efficacy of PRP in treatment of androgenic alopecia.

MATERIALS AND METHODS

Ten patients were given autologous PRP injections on the affected area of alopecia over a period of 3 months at interval of 2-3 weeks and results were assessed.

RESULTS

Three months after the treatment, the patients presented clinical improvement in the hair counts, hair thickness, hair root strength, and overall alopecia.

CONCLUSION

PRP appears to be a cheap, effective, and promising therapy for androgenic alopecia with no major adverse effects.

摘要

背景

富血小板血浆(PRP)在雄激素性脱发的治疗中显示出显著的有益效果,且无任何重大不良反应。活化的自体PRP中的生长因子可诱导真皮乳头细胞增殖。

目的

研究PRP治疗雄激素性脱发的临床疗效。

材料与方法

10例患者在3个月内每隔2 - 3周在脱发患处注射自体PRP,并对结果进行评估。

结果

治疗3个月后,患者在毛发数量、毛发厚度、发根强度和整体脱发情况方面均有临床改善。

结论

PRP似乎是一种治疗雄激素性脱发的廉价、有效且有前景的疗法,无重大不良反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/447d/4562137/ceaa861ead0b/AJTS-9-159-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/447d/4562137/4e01714b1e43/AJTS-9-159-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/447d/4562137/e1574028763e/AJTS-9-159-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/447d/4562137/1c9e04e04338/AJTS-9-159-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/447d/4562137/ceaa861ead0b/AJTS-9-159-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/447d/4562137/4e01714b1e43/AJTS-9-159-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/447d/4562137/e1574028763e/AJTS-9-159-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/447d/4562137/1c9e04e04338/AJTS-9-159-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/447d/4562137/ceaa861ead0b/AJTS-9-159-g005.jpg

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A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet-rich plasma on alopecia areata.一项随机、双盲、安慰剂和阳性对照、半头研究,评估富血小板血浆对斑秃的疗效。
Br J Dermatol. 2013 Sep;169(3):690-4. doi: 10.1111/bjd.12397.
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Amyopathic dermatomyositis-associated bilateral elbow ulcers successfully treated with autologous platelet-rich plasma.采用自体富血小板血浆成功治疗无肌病性皮肌炎相关的双侧肘部溃疡。
Int J Dermatol. 2014 Jan;53(1):e50-2. doi: 10.1111/j.1365-4632.2012.05588.x. Epub 2013 Mar 3.
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Letter: autologous fat grafting and platelet-rich plasma for treatment of facial contour defects.
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J Cutan Aesthet Surg. 2023 Jul-Sep;16(3):169-177. doi: 10.4103/JCAS.JCAS_206_22.
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Biotherapeutic Applications of Platelet-Rich Plasma in Regenerative Medicine.富血小板血浆在再生医学中的生物治疗应用。
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