来自巴西累西腓一名家庭护理患者的产KPC的粘质沙雷氏菌
KPC-PRODUCING Serratia marcescens IN A HOME-CARE PATIENT FROM RECIFE, BRAZIL.
作者信息
Margate Emmily, Magalhães Vera, Fehlberg Lorena Cristina Corrêa, Gales Ana Cristina, Lopes Ana Catarina Souza
机构信息
Departamento de Medicina Tropical, Universidade Federal de Pernambuco, Recife, PE, BR.
Universidade Federal de São Paulo, Sâo Paulo, SP, BR.
出版信息
Rev Inst Med Trop Sao Paulo. 2015 Jul-Aug;57(4):359-60. doi: 10.1590/S0036-46652015000400016.
Abstract
In this brief communication we describe the occurrence of a KPC-producing Serratia marcescens isolate in a home-care patient from Recife, Brazil. The blaKPC, blaSPM, blaIMP, blaVIM, blaOXA, blaCTX-M, blaSHV, blaTEM and blaGES genes were investigated by Polymerase Chain Reaction (PCR) and DNA sequencing. The isolate was positive for blaKPC-2 and blaTEM-1 and was resistant to aztreonam, cefepime, cefotaxime, imipenem, meropenem, gentamicin, ciprofloxacin and cefazidime, and susceptible only to amikacin, tigecycline and gatifloxacin. This is the first report in Brazil of KPC-producing S. marcescens clinical isolate outside of a hospital environment. Caregivers should be alert for the presence of this isolate in the community setting.
摘要
在本简短通讯中，我们描述了从巴西累西腓的一名家庭护理患者中分离出一株产KPC的粘质沙雷氏菌。通过聚合酶链反应（PCR）和DNA测序对blaKPC、blaSPM、blaIMP、blaVIM、blaOXA、blaCTX - M、blaSHV、blaTEM和blaGES基因进行了研究。该分离株blaKPC - 2和blaTEM - 1呈阳性，对氨曲南、头孢吡肟、头孢噻肟、亚胺培南、美罗培南、庆大霉素、环丙沙星和头孢唑林耐药，仅对阿米卡星、替加环素和加替沙星敏感。这是巴西首次报道在医院环境外分离出产KPC的粘质沙雷氏菌临床菌株。护理人员应警惕社区环境中存在这种分离株。
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