在巴西一家教学医院爆发的耐碳青霉烯类粘质沙雷氏菌分离株中KPC-2和IMP-10的共同产生
Coproduction of KPC-2 and IMP-10 in Carbapenem-Resistant Serratia marcescens Isolates from an Outbreak in a Brazilian Teaching Hospital.
作者信息
Silva Kesia Esther, Cayô Rodrigo, Carvalhaes Cecilia Godoy, Patussi Correia Sacchi Flávia, Rodrigues-Costa Fernanda, Ramos da Silva Ana Carolina, Croda Julio, Gales Ana Cristina, Simionatto Simone
机构信息
Laboratório de Pesquisa em Ciências da Saúde, Universidade Federal da Grande Dourados (UFGD), Dourados, Mato Grasso do Sul, Brazil.
Laboratório ALERTA, Disciplina de Infectologia, Departamento de Medicina, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
出版信息
J Clin Microbiol. 2015 Jul;53(7):2324-8. doi: 10.1128/JCM.00727-15. Epub 2015 Apr 15.
Abstract
We describe an outbreak caused by KPC-2- and IMP-10-producing Serratia marcescens isolates in a Brazilian teaching hospital. Tigecycline was the only active antimicrobial agent tested. The blaIMP-10 gene was located in a new class 1 integron, named In990, carried by a nonconjugative plasmid, in contrast to blaKPC-2.
摘要
我们描述了巴西一家教学医院中由产KPC-2和IMP-10的粘质沙雷氏菌分离株引起的一次暴发。替加环素是唯一经测试有活性的抗菌药物。与blaKPC-2不同，blaIMP-10基因位于一个新的1类整合子（命名为In990）中，该整合子由一个非接合性质粒携带。
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