芴甲氧羰基固相肽合成
Fmoc Solid-Phase Peptide Synthesis.
作者信息
Hansen Paul R, Oddo Alberto
机构信息
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
出版信息
Methods Mol Biol. 2015;1348:33-50. doi: 10.1007/978-1-4939-2999-3_5.
PMID:26424261
Abstract
Synthetic peptides are important as drugs and in research. Currently, the method of choice for producing these compounds is solid-phase peptide synthesis. In this nonspecialist review, we describe the scope and limitations of Fmoc solid-phase peptide synthesis. Furthermore, we provide a detailed protocol for Fmoc peptide synthesis.
摘要
合成肽作为药物和用于研究都很重要。目前，生产这些化合物的首选方法是固相肽合成。在这篇非专业综述中，我们描述了芴甲氧羰基（Fmoc）固相肽合成的范围和局限性。此外，我们提供了一份Fmoc肽合成的详细方案。
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