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使用caNanoLab支持癌症纳米技术数据结构化收集的经验。

Experiences in supporting the structured collection of cancer nanotechnology data using caNanoLab.

作者信息

Morris Stephanie A, Gaheen Sharon, Lijowski Michal, Heiskanen Mervi, Klemm Juli

机构信息

Office of Cancer Nanotechnology Research, National Cancer Institute/NIH, 31 Center Drive, Bethesda, MD, 20892, USA.

Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, 8560 Progress Drive, Frederick, MD, 21701, USA.

出版信息

Beilstein J Nanotechnol. 2015 Jul 21;6:1580-93. doi: 10.3762/bjnano.6.161. eCollection 2015.

DOI:10.3762/bjnano.6.161
PMID:26425409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4578394/
Abstract

The cancer Nanotechnology Laboratory (caNanoLab) data portal is an online nanomaterial database that allows users to submit and retrieve information on well-characterized nanomaterials, including composition, in vitro and in vivo experimental characterizations, experimental protocols, and related publications. Initiated in 2006, caNanoLab serves as an established resource with an infrastructure supporting the structured collection of nanotechnology data to address the needs of the cancer biomedical and nanotechnology communities. The portal contains over 1,000 curated nanomaterial data records that are publicly accessible for review, comparison, and re-use, with the ultimate goal of accelerating the translation of nanotechnology-based cancer therapeutics, diagnostics, and imaging agents to the clinic. In this paper, we will discuss challenges associated with developing a nanomaterial database and recognized needs for nanotechnology data curation and sharing in the biomedical research community. We will also describe the latest version of caNanoLab, caNanoLab 2.0, which includes enhancements and new features to improve usability such as personalized views of data and enhanced search and navigation.

摘要

癌症纳米技术实验室（caNanoLab）数据门户是一个在线纳米材料数据库，用户可以在其中提交和检索有关特征明确的纳米材料的信息，包括组成、体外和体内实验表征、实验方案以及相关出版物。caNanoLab于2006年启动，是一个成熟的资源库，拥有支持纳米技术数据结构化收集的基础设施，以满足癌症生物医学和纳米技术领域的需求。该门户包含1000多条经过整理的纳米材料数据记录，可供公众查阅、比较和重复使用，其最终目标是加速基于纳米技术的癌症治疗、诊断和成像剂向临床的转化。在本文中，我们将讨论开发纳米材料数据库所面临的挑战以及生物医学研究界对纳米技术数据管理和共享的公认需求。我们还将介绍caNanoLab的最新版本caNanoLab 2.0，它包括增强功能和新特性，以提高可用性，如数据的个性化视图以及增强的搜索和导航功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c622/4578394/9f1042950b79/Beilstein_J_Nanotechnol-06-1580-g014.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c622/4578394/d3399af6e9a4/Beilstein_J_Nanotechnol-06-1580-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c622/4578394/d230cd74fa61/Beilstein_J_Nanotechnol-06-1580-g008.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c622/4578394/e32b35c236a2/Beilstein_J_Nanotechnol-06-1580-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c622/4578394/ca6a97fa31ff/Beilstein_J_Nanotechnol-06-1580-g011.jpg
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