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皮肤辐射综合征的重建剂量测定法。

Reconstructive dosimetry for cutaneous radiation syndrome.

作者信息

Lima C M A, Lima A R, Degenhardt Ä L, Valverde N J, Silva F C A da

机构信息

Instituto de Radioproteção e Dosimetria, Instituto de Pesquisas Energéticas e Nucleares, Rio de Janeiro, RJ, BR.

Fundação Eletronuclear de Assistência Médica, Rio de Janeiro, RJ, BR.

出版信息

Braz J Med Biol Res. 2015 Oct;48(10):895-901. doi: 10.1590/1414-431X20144337. Epub 2015 May 8.

Abstract

According to the International Atomic Energy Agency (IAEA), a relatively significant number of radiological accidents have occurred in recent years mainly because of the practices referred to as potentially high-risk activities, such as radiotherapy, large irradiators and industrial radiography, especially in gammagraphy assays. In some instances, severe injuries have occurred in exposed persons due to high radiation doses. In industrial radiography, 80 cases involving a total of 120 radiation workers, 110 members of the public including 12 deaths have been recorded up to 2014. Radiological accidents in industrial practices in Brazil have mainly resulted in development of cutaneous radiation syndrome (CRS) in hands and fingers. Brazilian data include 5 serious cases related to industrial gammagraphy, affecting 7 radiation workers and 19 members of the public; however, none of them were fatal. Some methods of reconstructive dosimetry have been used to estimate the radiation dose to assist in prescribing medical treatment. The type and development of cutaneous manifestations in the exposed areas of a person is the first achievable gross dose estimation. This review article presents the state-of-the-art reconstructive dosimetry methods enabling estimation of local radiation doses and provides guidelines for medical handling of the exposed individuals. The review also presents the Chilean and Brazilian radiological accident cases to highlight the importance of reconstructive dosimetry.

摘要

根据国际原子能机构(IAEA)的数据,近年来发生了相当数量的放射事故,主要是由于被称为潜在高风险活动的操作,如放射治疗、大型辐照器和工业射线照相,特别是在γ射线照相检测中。在某些情况下,受照人员因高辐射剂量而受到严重伤害。在工业射线照相方面,截至2014年,已记录了80起事故,涉及总共120名辐射工作人员以及包括12人死亡在内的110名公众。巴西工业实践中的放射事故主要导致手部和手指出现皮肤辐射综合征(CRS)。巴西的数据包括5起与工业γ射线照相相关的严重事故,涉及7名辐射工作人员和19名公众;然而,这些事故均无人员死亡。一些重建剂量测定方法已被用于估计辐射剂量,以协助制定医疗治疗方案。一个人暴露部位皮肤表现的类型和发展情况是初步可实现的总体剂量估计。这篇综述文章介绍了能够估计局部辐射剂量的最新重建剂量测定方法,并为受照个体的医疗处理提供了指导方针。该综述还介绍了智利和巴西的放射事故案例,以突出重建剂量测定的重要性。

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