Bessa G, Melo-Reis P R, Araújo L A, Mrué F, Freitas G B, Brandão M L, Silva Júnior N J
Pró-Reitoria de Pós-graduação e Pesquisa, Pontifícia Universidade Católica de Goiás, Goiânia, GO, BR.
Programa de Pós-graduação em Ciências Ambientais e Saúde, Departamento de Biomedicina e Farmácia, Pontifícia Universidade Católica de Goiás, Goiânia, GO, BR.
Braz J Biol. 2015 Aug;75(3):752-8. doi: 10.1590/1519-6984.01214. Epub 2015 Aug 25.
To assess the pro-angiogenic activity of Euphorbia tirucalli, commonly known as "avelós" plant, we performed a series of tests by applying an aqueous E. tirucalli latex solution (10 mg/mL) to the chorioallantoic membranes (CAMs) of 80 fertilized chicken eggs incubated in a temperature- and humidity-controlled automatic incubator. The results indicated that the aqueous latex solution increased vascular network formation compared to that with the negative control (p < 0.05) and the inhibitor control (p < 0.05). This suggests that under the experimental conditions tested, the aqueous latex solution induced an inflammatory response leading to neoangiogenesis.
为评估通常被称为“阿韦洛斯”植物的绿玉树的促血管生成活性，我们进行了一系列试验，即将绿玉树乳胶水溶液（10毫克/毫升）应用于在温度和湿度可控的自动孵化器中孵化的80枚受精鸡蛋的绒毛尿囊膜（CAMs）上。结果表明，与阴性对照（p < 0.05）和抑制剂对照（p < 0.05）相比，乳胶水溶液增加了血管网络的形成。这表明在所测试的实验条件下，乳胶水溶液诱导了导致新生血管形成的炎症反应。
