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实现世界卫生组织对临床药理学的愿景。

Achieving the World Health Organization's vision for clinical pharmacology.

作者信息

Martin Jennifer H, Henry David, Gray Jean, Day Richard, Bochner Felix, Ferro Albert, Pirmohamed Munir, Mörike Klaus, Schwab Matthias

机构信息

Discipline of Clinical Pharmacology, University of Newcastle, Australia.

Department Clinical Pharmacology, University Hospital Tübingen, Germany.

出版信息

Br J Clin Pharmacol. 2016 Feb;81(2):223-7. doi: 10.1111/bcp.12803. Epub 2015 Nov 23.

DOI:10.1111/bcp.12803
PMID:26466826
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4833156/
Abstract

Clinical pharmacology is a medical specialty whose practitioners teach, undertake research, frame policy, give information and advice about the actions and proper uses of medicines in humans and implement that knowledge in clinical practice. It involves a combination of several activities: drug discovery and development, training safe prescribers, providing objective and evidence-based therapeutic information to ethics, regulatory and pricing bodies, supporting patient care in an increasingly subspecialized arena where co-morbidities, polypharmacy, altered pharmacokinetics and drug interactions are common and developing and contributing to medicines policies for Governments. Clinical pharmacologists must advocate drug quality and they must also advocate for sustainability of the Discipline. However for this they need appropriate clinical service and training support. This Commentary discusses strategies to ensure the Discipline is supported by teaching, training and policy organizations, to communicate the full benefits of clinical pharmacology services, put a monetary value on clinical pharmacology services and to grow the clinical pharmacology workforce to support a growing clinical, academic and regulatory need.

摘要

临床药理学是一门医学专业,其从业者进行教学、开展研究、制定政策、提供有关药物在人体中的作用及合理使用的信息和建议,并将这些知识应用于临床实践。它涉及多种活动的结合:药物研发、培训安全开药者、向伦理、监管和定价机构提供客观且基于证据的治疗信息、在合并症、多药联用、药代动力学改变和药物相互作用常见的日益专业化的领域支持患者护理,以及为政府制定和推动药品政策。临床药理学家必须倡导药物质量,他们还必须倡导该学科的可持续发展。然而,为此他们需要适当的临床服务和培训支持。本评论讨论了确保该学科得到教学、培训和政策组织支持的策略,以传达临床药理学服务的全部益处,为临床药理学服务赋予货币价值,并增加临床药理学劳动力以满足不断增长的临床、学术和监管需求。

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2
Choosing Wisely in the UK: the Academy of Medical Royal Colleges' initiative to reduce the harms of too much medicine.英国的明智选择:皇家医学院学会减少过度医疗危害的倡议。
BMJ. 2015 May 12;350:h2308. doi: 10.1136/bmj.h2308.
3
Data collection as a barrier to personalized medicine.数据收集是个性化医疗的障碍。
Trends Pharmacol Sci. 2015 Feb;36(2):68-71. doi: 10.1016/j.tips.2014.11.002. Epub 2014 Dec 2.
4
Personalized pharmacogenomics: predicting efficacy and adverse drug reactions.个性化药物基因组学:预测疗效和药物不良反应
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Clinical Pharmacology in European health care-outcome of a questionnaire study in 31 countries.欧洲医疗保健中的临床药理学——31 个国家问卷调查研究的结果。
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