Pês Tanise S, Saccol Etiane M H, Ourique Giovana M, Londero Érika P, Gressler Luciane T, Finamor Isabela A, Rotili Daniel A, Golombieski Jaqueline I, Glanzner Werner G, Llesuy Susana F, Gonçalves Paulo B D, Radünz Neto João, Baldisserotto Bernardo, Pavanato Maria A
Fish Physiol Biochem. 2016 Feb;42(1):321-33. doi: 10.1007/s10695-015-0140-z.
The effects of adding rutin to the diet (0, 0.15 or 0.30%) of silver catfish for 21 days on blood parameters, oxidative stress biomarkers and pituitary hormones expression were investigated. Fish that received the diet containing 0.15% rutin exhibited reduced plasma cortisol levels. The levels of lipid peroxidation were lowered in the all tissues of animals receiving the diet containing rutin. Rutin increased the activity of the superoxide dismutase (SOD), catalase (CAT), nonprotein thiols (NPSH), ascorbic acid content (AA) and total reactive antioxidant potential (TRAP) in the brain; glutathione S-transferase (GST) activity and TRAP in the gills; SOD, CAT and GST activity, NPSH, AA levels and TRAP in the liver; CAT and GST activity and TRAP levels in the kidneys; and glutathione peroxidase activity, NPSH, AA levels and TRAP in the muscle. There were no changes regarding the expression of growth hormone, prolactin and somatolactin in fish fed with the diet containing rutin when compared with the control. The supplementation of rutin to the diet of fish is beneficial because it increases the antioxidant responses of tissues.
研究了在21天内给胡子鲶日粮中添加芦丁（0%、0.15%或0.30%）对血液参数、氧化应激生物标志物和垂体激素表达的影响。接受含0.15%芦丁日粮的鱼血浆皮质醇水平降低。接受含芦丁日粮的动物所有组织中的脂质过氧化水平均降低。芦丁增加了大脑中超氧化物歧化酶（SOD）、过氧化氢酶（CAT）、非蛋白硫醇（NPSH）、抗坏血酸含量（AA）和总反应性抗氧化潜力（TRAP）的活性；鳃中谷胱甘肽S-转移酶（GST）活性和TRAP；肝脏中SOD、CAT和GST活性、NPSH、AA水平和TRAP；肾脏中CAT和GST活性以及TRAP水平；肌肉中谷胱甘肽过氧化物酶活性、NPSH、AA水平和TRAP。与对照组相比，饲喂含芦丁日粮的鱼中生长激素、催乳素和生长抑素的表达没有变化。在鱼的日粮中添加芦丁是有益的，因为它增加了组织的抗氧化反应。
