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慢性乙醇作用对椭圆酵母变种酿酒酵母中一般氨基酸通透酶活性的影响。

Effect of the chronic ethanol action on the activity of the general amino-acid permease from Saccharomyces cerevisiae var. ellipsoideus.

作者信息

Ferreras J M, Iglesias R, Girbés T

机构信息

Departamento de Bioquímica, Biología Molecular y Fisiología, Facultad de Ciencias, Universidad de Valladolid, Spain.

出版信息

Biochim Biophys Acta. 1989 Mar 13;979(3):375-7. doi: 10.1016/0005-2736(89)90260-5.

DOI:10.1016/0005-2736(89)90260-5
PMID:2647148
Abstract

The presence of ethanol and cycloheximide during growth were found to inhibit the function of the general amino-acid permease of Saccharomyces cerevisiae var. ellipsoideus. Contrary to cycloheximide, the effect of ethanol upon growth in alcohol-free medium was reversible. The effect of both inhibitors could be explained in terms of reduction of the number of active carrier molecules located in the plasma membrane.

摘要

研究发现,酿酒酵母椭圆变种在生长过程中存在乙醇和环己酰亚胺会抑制其通用氨基酸通透酶的功能。与环己酰亚胺不同,乙醇对在无酒精培养基中生长的影响是可逆的。两种抑制剂的作用都可以通过位于质膜上的活性载体分子数量减少来解释。

相似文献

1
Effect of the chronic ethanol action on the activity of the general amino-acid permease from Saccharomyces cerevisiae var. ellipsoideus.慢性乙醇作用对椭圆酵母变种酿酒酵母中一般氨基酸通透酶活性的影响。
Biochim Biophys Acta. 1989 Mar 13;979(3):375-7. doi: 10.1016/0005-2736(89)90260-5.
2
Effect of L-azetidine 2-carboxilic acid on the activity of the general amino-acid permease from Saccharomyces cerevisiae var. ellipsoideus.L-氮杂环丁烷-2-羧酸对椭圆酵母普通氨基酸通透酶活性的影响。
Arch Microbiol. 1991;155(4):320-4. doi: 10.1007/BF00243449.
3
Changes in membrane proteins associated with inhibition of the general amino acid permease of yeast (Saccharomyces cerevisiae).与酵母(酿酒酵母)通用氨基酸通透酶抑制相关的膜蛋白变化
Biochem J. 1981 May 15;196(2):531-6. doi: 10.1042/bj1960531.
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Differential D-glucose requirements of the general amino-acid permease and protein synthesis in Saccharomyces cerevisiae var. ellipsoideus.椭圆酵母中普通氨基酸通透酶的不同D-葡萄糖需求与蛋白质合成
Cell Mol Biol. 1990;36(5):581-7.
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Study of the positive control of the general amino-acid permease and other ammonia-sensitive uptake systems by the product of the NPR1 gene in the yeast Saccharomyces cerevisiae.酿酒酵母中NPR1基因产物对一般氨基酸通透酶及其他氨敏感摄取系统的正向调控研究。
Eur J Biochem. 1983 Jun 1;133(1):141-4. doi: 10.1111/j.1432-1033.1983.tb07439.x.
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Effect of continued exposition to ethanol on activity of the ammonium and fructose transport systems in Saccharomyces cerevisiae var. ellipsoideus.持续暴露于乙醇对椭圆酿酒酵母氨和果糖运输系统活性的影响。
Biotechnol Bioeng. 1991 Feb 20;37(4):389-91. doi: 10.1002/bit.260370415.
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["Cellular memory" linked to retroinhibition of general amino acid permease in Saccharomyces cerevisiae].["细胞记忆"与酿酒酵母中通用氨基酸通透酶的反馈抑制相关]
Arch Int Physiol Biochim. 1972 Jan;80(1):184-5.
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[Effect of ammonium ions on the uptake of L-leucine in Saccharomyces cerevisiae. Repression and inhibition of transport systems].[铵离子对酿酒酵母中L-亮氨酸摄取的影响。转运系统的阻遏与抑制]
Rev Argent Microbiol. 1990 Jan-Mar;22(1):7-16.
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Control of the general amino acid permease of Penicillium chrysogenum by transinhibition and turnover.产黄青霉一般氨基酸通透酶的反式抑制和周转调控
Arch Biochem Biophys. 1973 Jan;154(1):387-99. doi: 10.1016/0003-9861(73)90071-4.
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Changes in the activity of the general amino acid permease from Saccharomyces cerevisiae var. ellipsoideus during fermentation.酿酒酵母椭圆变种中一般氨基酸通透酶活性在发酵过程中的变化。
Biotechnol Bioeng. 1990 Oct 20;36(8):808-10. doi: 10.1002/bit.260360808.

引用本文的文献

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Auxotrophic Mutations Reduce Tolerance of Saccharomyces cerevisiae to Very High Levels of Ethanol Stress.营养缺陷型突变降低酿酒酵母对极高水平乙醇胁迫的耐受性。
Eukaryot Cell. 2015 Sep;14(9):884-97. doi: 10.1128/EC.00053-15. Epub 2015 Jun 26.
2
Comparative polygenic analysis of maximal ethanol accumulation capacity and tolerance to high ethanol levels of cell proliferation in yeast.酵母中最大乙醇积累能力和耐受高乙醇水平细胞增殖的比较多基因分析。
PLoS Genet. 2013 Jun;9(6):e1003548. doi: 10.1371/journal.pgen.1003548. Epub 2013 Jun 6.
3
Impaired uptake and/or utilization of leucine by Saccharomyces cerevisiae is suppressed by the SPT15-300 allele of the TATA-binding protein gene.
酿酒酵母对亮氨酸摄取和/或利用的受损情况,被TATA结合蛋白基因的SPT15 - 300等位基因所抑制。
Appl Environ Microbiol. 2009 Oct;75(19):6055-61. doi: 10.1128/AEM.00989-09. Epub 2009 Aug 7.
4
Effect of L-azetidine 2-carboxilic acid on the activity of the general amino-acid permease from Saccharomyces cerevisiae var. ellipsoideus.L-氮杂环丁烷-2-羧酸对椭圆酵母普通氨基酸通透酶活性的影响。
Arch Microbiol. 1991;155(4):320-4. doi: 10.1007/BF00243449.