Ferreras J M, Iglesias R, Girbés T
Departamento de Bioquímica, Biología Molecular y Fisiología, Facultad de Ciencias, Universidad de Valladolid, Spain.
Biochim Biophys Acta. 1989 Mar 13;979(3):375-7. doi: 10.1016/0005-2736(89)90260-5.
The presence of ethanol and cycloheximide during growth were found to inhibit the function of the general amino-acid permease of Saccharomyces cerevisiae var. ellipsoideus. Contrary to cycloheximide, the effect of ethanol upon growth in alcohol-free medium was reversible. The effect of both inhibitors could be explained in terms of reduction of the number of active carrier molecules located in the plasma membrane.
研究发现,酿酒酵母椭圆变种在生长过程中存在乙醇和环己酰亚胺会抑制其通用氨基酸通透酶的功能。与环己酰亚胺不同,乙醇对在无酒精培养基中生长的影响是可逆的。两种抑制剂的作用都可以通过位于质膜上的活性载体分子数量减少来解释。