• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

生物医学中的生物聚合物及其在生物医学科学中的起源与演变:一项系统综述

Biomedical Biopolymers, their Origin and Evolution in Biomedical Sciences: A Systematic Review.

作者信息

Yadav Preeti, Yadav Harsh, Shah Veena Gowri, Shah Gaurav, Dhaka Gaurav

机构信息

Senior Lecturer, Department of Prosthodontics, Crown and Bridge and Implantology, NIMS Dental College , Jaipur, Rajasthan, India .

Private Practioner, Oral & Maxillofacial Surgery, Gurgaon, Haryana, India .

出版信息

J Clin Diagn Res. 2015 Sep;9(9):ZE21-5. doi: 10.7860/JCDR/2015/13907.6565. Epub 2015 Sep 1.

DOI:10.7860/JCDR/2015/13907.6565
PMID:26501034
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4606363/
Abstract

Biopolymers provide a plethora of applications in the pharmaceutical and medical applications. A material that can be used for biomedical applications like wound healing, drug delivery and tissue engineering should possess certain properties like biocompatibility, biodegradation to non-toxic products, low antigenicity, high bio-activity, processability to complicated shapes with appropriate porosity, ability to support cell growth and proliferation and appropriate mechanical properties, as well as maintaining mechanical strength. This paper reviews biodegradable biopolymers focusing on their potential in biomedical applications. Biopolymers most commonly used and most abundantly available have been described with focus on the properties relevant to biomedical importance.

摘要

生物聚合物在制药和医学应用中有大量的应用。一种可用于诸如伤口愈合、药物递送和组织工程等生物医学应用的材料应具备某些特性,如生物相容性、降解为无毒产物、低抗原性、高生物活性、可加工成具有适当孔隙率的复杂形状、支持细胞生长和增殖的能力以及适当的机械性能,同时还要保持机械强度。本文综述了可生物降解生物聚合物,重点关注它们在生物医学应用中的潜力。已对最常用和最丰富可得的生物聚合物进行了描述,重点是与生物医学重要性相关的特性。

相似文献

1
Biomedical Biopolymers, their Origin and Evolution in Biomedical Sciences: A Systematic Review.生物医学中的生物聚合物及其在生物医学科学中的起源与演变:一项系统综述
J Clin Diagn Res. 2015 Sep;9(9):ZE21-5. doi: 10.7860/JCDR/2015/13907.6565. Epub 2015 Sep 1.
2
Bio-Based Electrospun Fibers for Wound Healing.用于伤口愈合的生物基电纺纤维。
J Funct Biomater. 2020 Sep 22;11(3):67. doi: 10.3390/jfb11030067.
3
Application of plant products in the synthesis and functionalisation of biopolymers.植物产物在生物聚合物的合成和功能化中的应用。
Int J Biol Macromol. 2023 May 15;237:124174. doi: 10.1016/j.ijbiomac.2023.124174. Epub 2023 Mar 27.
4
Polylactic acid: synthesis and biomedical applications.聚乳酸:合成与生物医学应用。
J Appl Microbiol. 2019 Dec;127(6):1612-1626. doi: 10.1111/jam.14290. Epub 2019 Jun 17.
5
Medical applications of biopolymer nanofibers.生物聚合物纳米纤维的医学应用。
Biomater Sci. 2022 Jul 26;10(15):4107-4118. doi: 10.1039/d2bm00701k.
6
Biocompatible Polymers and their Potential Biomedical Applications: A Review.生物相容性聚合物及其在生物医学中的潜在应用:综述。
Curr Pharm Des. 2019;25(34):3608-3619. doi: 10.2174/1381612825999191011105148.
7
Novel chitin and chitosan nanofibers in biomedical applications.用于生物医学应用的新型壳聚糖和壳聚糖纳米纤维。
Biotechnol Adv. 2010 Jan-Feb;28(1):142-50. doi: 10.1016/j.biotechadv.2009.11.001.
8
Biopolymer Microparticles Prepared by Microfluidics for Biomedical Applications.微流控技术制备用于生物医学应用的生物聚合物微球。
Small. 2020 Mar;16(9):e1903736. doi: 10.1002/smll.201903736. Epub 2019 Sep 26.
9
Chitosan functionalized poly(vinyl alcohol) for prospects biomedical and industrial applications: A review.壳聚糖功能化聚乙烯醇在生物医学和工业应用中的前景:综述。
Int J Biol Macromol. 2016 Jun;87:141-54. doi: 10.1016/j.ijbiomac.2016.02.035. Epub 2016 Feb 15.
10
Insights into the Role of Biopolymer-Based Xerogels in Biomedical Applications.基于生物聚合物的干凝胶在生物医学应用中的作用洞察
Gels. 2022 May 29;8(6):334. doi: 10.3390/gels8060334.

引用本文的文献

1
Next-Generation Wound Healing Materials: Role of Biopolymers and Their Composites.下一代伤口愈合材料:生物聚合物及其复合材料的作用。
Polymers (Basel). 2025 Aug 19;17(16):2244. doi: 10.3390/polym17162244.
2
Chitosan-tripolyphosphate-tannic acid cryogels as a biocompatible adsorbent for the removal of Cu ions.壳聚糖-三聚磷酸钠-单宁酸冷冻凝胶作为一种用于去除铜离子的生物相容性吸附剂。
R Soc Open Sci. 2025 Aug 6;12(8):242274. doi: 10.1098/rsos.242274. eCollection 2025 Aug.
3
Biomaterials in Postoperative Adhesion Barriers and Uterine Tissue Engineering.术后粘连屏障及子宫组织工程中的生物材料
Gels. 2025 Jun 9;11(6):441. doi: 10.3390/gels11060441.
4
Failure or future? Exploring alternative antibacterials: a comparative analysis of antibiotics and naturally derived biopolymers.失败还是未来?探索替代抗菌剂:抗生素与天然衍生生物聚合物的比较分析
Front Microbiol. 2025 Feb 3;16:1526250. doi: 10.3389/fmicb.2025.1526250. eCollection 2025.
5
Novel Nanozyme-Based Multicomponent in situ Hydrogels with Antibacterial, Hypoxia-Relieving and Proliferative Properties for Promoting Gastrostomy Tube Tract Maturation.具有抗菌、缓解缺氧和增殖特性的新型基于纳米酶的多组分原位水凝胶促进胃造口管通道成熟
Int J Nanomedicine. 2025 Jan 21;20:827-848. doi: 10.2147/IJN.S496537. eCollection 2025.
6
Biopolymer encapsulation for improved probiotic delivery: Advancements and challenges.用于改善益生菌递送的生物聚合物包封:进展与挑战。
AIMS Microbiol. 2024 Nov 15;10(4):986-1023. doi: 10.3934/microbiol.2024043. eCollection 2024.
7
Recycling Technologies for Biopolymers: Current Challenges and Future Directions.生物聚合物的回收技术:当前挑战与未来方向
Polymers (Basel). 2024 Sep 30;16(19):2770. doi: 10.3390/polym16192770.
8
Bioarchitectural Design of Bioactive Biopolymers: Structure-Function Paradigm for Diabetic Wound Healing.生物活性生物聚合物的生物架构设计:糖尿病伤口愈合的结构-功能范式
Biomimetics (Basel). 2024 May 4;9(5):275. doi: 10.3390/biomimetics9050275.
9
Time-Temperature Superposition of the Dissolution of Wool Yarns in the Ionic Liquid 1-Ethyl-3-methylimidazolium Acetate.羊毛纱线在离子液体1-乙基-3-甲基咪唑醋酸盐中溶解的时间-温度叠加
Materials (Basel). 2024 Jan 2;17(1):244. doi: 10.3390/ma17010244.
10
A review on the recent applications of synthetic biopolymers in 3D printing for biomedical applications.关于合成生物聚合物在生物医学应用的 3D 打印中的最新应用的综述。
J Mater Sci Mater Med. 2023 Nov 20;34(12):62. doi: 10.1007/s10856-023-06765-9.

本文引用的文献

1
Controlling Degradation of Hydrogels via the Size of Cross-Linked Junctions.通过交联节点大小控制水凝胶的降解
Adv Mater. 2004 Nov 30;16(21):1917-1921. doi: 10.1002/adma.200400014.
2
In situ injectable nano-composite hydrogel composed of curcumin, N,O-carboxymethyl chitosan and oxidized alginate for wound healing application.原位注射型载姜黄素纳米复合水凝胶,由姜黄素、N,O-羧甲基壳聚糖和氧化海藻酸钠组成,用于伤口愈合应用。
Int J Pharm. 2012 Nov 1;437(1-2):110-9. doi: 10.1016/j.ijpharm.2012.08.001. Epub 2012 Aug 7.
3
In vivo bioactivity of rhBMP-2 delivered with novel polyelectrolyte complexation shells assembled on an alginate microbead core template.新型聚电解质复合壳在海藻酸钠微球核模板上组装后递送 rhBMP-2 的体内生物活性。
J Control Release. 2012 Sep 10;162(2):364-72. doi: 10.1016/j.jconrel.2012.07.027. Epub 2012 Jul 27.
4
Photodegradable iron(III) cross-linked alginate gels.可光降解的三价铁交联海藻酸盐凝胶。
Biomacromolecules. 2012 Aug 13;13(8):2465-71. doi: 10.1021/bm300707a. Epub 2012 Jul 25.
5
The visualisation and speed of kill of wound isolates on a silver alginate dressing.银藻酸盐敷料对伤口分离物的可视化和杀菌速度。
Int Wound J. 2012 Dec;9(6):633-42. doi: 10.1111/j.1742-481X.2012.00927.x. Epub 2012 Mar 8.
6
Early use of negative pressure therapy in combination with silver dressings in a difficult breast abscess.早期使用负压治疗联合银敷料治疗困难性乳房脓肿。
Int Wound J. 2011 Dec;8(6):608-11. doi: 10.1111/j.1742-481X.2011.00838.x. Epub 2011 Aug 31.
7
Antimicrobial properties of chitosan and mode of action: a state of the art review.壳聚糖的抗菌性能及其作用模式:综述。
Int J Food Microbiol. 2010 Nov 15;144(1):51-63. doi: 10.1016/j.ijfoodmicro.2010.09.012. Epub 2010 Oct 15.
8
Chitosan effect on dental enamel de-remineralization: an in vitro evaluation.壳聚糖对牙釉质脱矿的影响:体外评价。
J Dent. 2010 Nov;38(11):848-52. doi: 10.1016/j.jdent.2010.06.004. Epub 2010 Jun 19.
9
Care of chronic wounds in palliative care and end-of-life patients.姑息治疗和终末期患者的慢性伤口护理。
Int Wound J. 2010 Aug;7(4):214-35. doi: 10.1111/j.1742-481X.2010.00682.x. Epub 2010 May 28.
10
Chitosan based polyelectrolyte complexes as potential carrier materials in drug delivery systems.壳聚糖基聚电解质复合物作为药物传递系统中的潜在载体材料。
Mar Drugs. 2010 Apr 19;8(4):1305-22. doi: 10.3390/md8041305.