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生物医学中的生物聚合物及其在生物医学科学中的起源与演变:一项系统综述

Biomedical Biopolymers, their Origin and Evolution in Biomedical Sciences: A Systematic Review.

作者信息

Yadav Preeti, Yadav Harsh, Shah Veena Gowri, Shah Gaurav, Dhaka Gaurav

机构信息

Senior Lecturer, Department of Prosthodontics, Crown and Bridge and Implantology, NIMS Dental College , Jaipur, Rajasthan, India .

Private Practioner, Oral & Maxillofacial Surgery, Gurgaon, Haryana, India .

出版信息

J Clin Diagn Res. 2015 Sep;9(9):ZE21-5. doi: 10.7860/JCDR/2015/13907.6565. Epub 2015 Sep 1.

Abstract

Biopolymers provide a plethora of applications in the pharmaceutical and medical applications. A material that can be used for biomedical applications like wound healing, drug delivery and tissue engineering should possess certain properties like biocompatibility, biodegradation to non-toxic products, low antigenicity, high bio-activity, processability to complicated shapes with appropriate porosity, ability to support cell growth and proliferation and appropriate mechanical properties, as well as maintaining mechanical strength. This paper reviews biodegradable biopolymers focusing on their potential in biomedical applications. Biopolymers most commonly used and most abundantly available have been described with focus on the properties relevant to biomedical importance.

摘要

生物聚合物在制药和医学应用中有大量的应用。一种可用于诸如伤口愈合、药物递送和组织工程等生物医学应用的材料应具备某些特性,如生物相容性、降解为无毒产物、低抗原性、高生物活性、可加工成具有适当孔隙率的复杂形状、支持细胞生长和增殖的能力以及适当的机械性能,同时还要保持机械强度。本文综述了可生物降解生物聚合物,重点关注它们在生物医学应用中的潜力。已对最常用和最丰富可得的生物聚合物进行了描述,重点是与生物医学重要性相关的特性。

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