Choi Jun-Ho, Seo Dong Wan
Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea.
Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Gut Liver. 2015 Nov 23;9(6):707-13. doi: 10.5009/gnl15077.
Since its introduction into clinical practice in the 1980s, endoscopic ultrasound (EUS) has been described as a good imaging modality for the diagnosis of pancreatobiliary diseases. However, differential diagnosis of certain lesions based only on B-mode ultrasound images can be challenging. Clinical use of ultrasound contrast agents has expanded the utility of EUS from that of detection to characterization of pancreatobiliary lesions based on the enhancement features of contrast-enhanced EUS (CE-EUS). Current low mechanical index techniques for CE-EUS using second-generation contrast agents have a number of distinct advantages over conventional diagnostic modalities in evaluating pancreatobiliary lesions, including real-time assessment of perfusion pattern, availability, and the absence of exposure to radiation. This article describes the technical aspects of CE-EUS and reviews the expanding indications in pancreatobiliary diseases and further development of this technique.
自20世纪80年代引入临床实践以来，内镜超声（EUS）一直被认为是诊断胰胆疾病的一种良好成像方式。然而，仅基于B超图像对某些病变进行鉴别诊断可能具有挑战性。超声造影剂的临床应用已将EUS的效用从检测扩展到基于超声造影增强内镜超声（CE-EUS）的增强特征对胰胆病变进行特征描述。目前使用第二代造影剂的CE-EUS低机械指数技术在评估胰胆病变方面比传统诊断方式具有许多明显优势，包括对灌注模式的实时评估、可用性以及无需暴露于辐射。本文介绍了CE-EUS的技术方面，并综述了其在胰胆疾病中不断扩大的适应证以及该技术的进一步发展。
