Zuo Lei, Zou Haidong, Zhang Jianhong, Fei Xinfeng, Xu Xun
Department of Ophthalmology, Shanghai General Hospital, Nanjing Medical University, Shanghai 200080, China ; Department of Ophthalmology, Branch of Shanghai First People's Hospital, Shanghai 200081, China.
Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China.
J Ophthalmol. 2015;2015:271425. doi: 10.1155/2015/271425. Epub 2015 Oct 7.
This cross-sectional study evaluated VRQOL in Chinese glaucoma patients and the potential factors influencing VRQOL. The VRQOL was assessed using the Chinese-version low vision quality of life questionnaire. Visual field loss was classified by the Hodapp-Parrish-Anderson method. The correlations of VRQOL to the best corrected visual acuity and the VF loss were investigated. The potential impact factors to VRQOL of glaucoma patients were screened by single factor analysis and were further analyzed by multiple regression analysis. There were significant differences in VRQOL scores between mild VF loss group and moderate VF loss group, moderate VF loss group and severe VF loss group, and mild VF loss group and severe VF loss group according to the better eye. In multiple linear regression, the binocular weighted average BCVA significantly affected the VRQOL scores. Binocular MD was the second influencing factor. In logistic regression, binocular severe VF loss and stroke were significantly associated with abnormal VRQOL. Education was the next influencing factor. This study showed that visual acuity correlated linearly with VRQOL, and VF loss might reach a certain level, correlating with abnormal VRQOL scores. Stroke was significantly associated with abnormal VRQOL.
这项横断面研究评估了中国青光眼患者的视觉相关生活质量(VRQOL)以及影响VRQOL的潜在因素。使用中文版低视力生活质量问卷对VRQOL进行评估。采用Hodapp-Parrish-Anderson方法对视野缺损进行分类。研究了VRQOL与最佳矫正视力及视野缺损之间的相关性。通过单因素分析筛选青光眼患者VRQOL的潜在影响因素,并进一步进行多元回归分析。根据较好眼,轻度视野缺损组与中度视野缺损组、中度视野缺损组与重度视野缺损组、轻度视野缺损组与重度视野缺损组之间的VRQOL评分存在显著差异。在多元线性回归中,双眼加权平均最佳矫正视力显著影响VRQOL评分。双眼平均缺损是第二个影响因素。在逻辑回归中,双眼严重视野缺损和中风与异常VRQOL显著相关。受教育程度是下一个影响因素。本研究表明,视力与VRQOL呈线性相关,视野缺损可能达到一定程度时,与异常VRQOL评分相关。中风与异常VRQOL显著相关。