Mojzis Peter, Studeny Pavel, Werner Liliana, Piñero David P
Eye Department, Regional Hospital Havlickuv Brod, Havlickuv Brod, Brod - Czech Republic.
Department of Ophthalmology, Medical Faculty of Charles University, Prague - Czech Republic.
Eur J Ophthalmol. 2016 Feb 15;26(2):e24-6. doi: 10.5301/ejo.5000704.
To describe the clinical and microscopic findings in 2 different patients of 2 cases of late opacification of the hydrophilic acrylic intraocular lens (IOL) Ioflex.
Two eyes of 2 patients (73 and 74 years old) had an uneventful phacoemulsification surgery with implantation of the Ioflex IOL (power +21.5 D). At 5 years after surgery, a dense IOL opacification was detected in both cases with significant visual degradation. The IOLs were explanted and analyzed by microscopy.
In both cases, a satisfactory visual recovery was achieved (corrected distance visual acuity of 6/9 and 6/12). Microscopic examination of the explanted IOLs revealed multiple small granules on the surface/subsurface of the lens. Although histochemical or surface analyses were not performed, the aspect appears consistent with a process of calcification of this lens design. Other findings included few surface contaminants, such as fibers, crystals that may correspond to dry viscoelastic and/or salt solutions, as well as pigments and dust-like deposits.
Opacification of the posterior chamber hydrophilic acrylic IOL Ioflex probably related to calcification can appear several years after its implantation and requires IOL exchange due to the significant visual loss induced. More studies are required to understand the causes of this complication.
描述2例使用亲水性丙烯酸人工晶状体（IOL）Ioflex后发生晚期混浊的不同患者的临床和显微镜检查结果。
2例患者（73岁和74岁）的2只眼睛在白内障超声乳化手术中顺利植入Ioflex人工晶状体（度数+21.5 D）。术后5年，2例均检测到人工晶状体出现致密混浊，视力显著下降。将人工晶状体取出并进行显微镜分析。
2例均实现了满意的视力恢复（矫正远视力分别为6/9和6/12）。对取出的人工晶状体进行显微镜检查发现，晶状体表面/亚表面有多个小颗粒。尽管未进行组织化学或表面分析，但外观似乎与这种晶状体设计的钙化过程一致。其他发现包括少量表面污染物，如纤维、可能对应于干燥粘弹剂和/或盐溶液的晶体，以及色素和粉尘样沉积物。
后房型亲水性丙烯酸人工晶状体Ioflex的混浊可能与钙化有关，可在植入数年之后出现，由于其导致明显视力丧失，故需要更换人工晶状体。需要更多研究来了解这种并发症的原因。
