冥想对膝关节骨关节炎症状的影响。

Effects of Meditation on Symptoms of Knee Osteoarthritis.

作者信息

Selfe Terry Kit, Innes Kim E

机构信息

Clinical research program manager in the department of epidemiology at West Virginia University School of Public Health in Morgantown, West Virginia, and is a clinical assistant professor at the Center for the Study of Complementary and Alternative Therapies, in the University of Virginia Health System, Charlottesville, Virginia.

Associate professor in the department of epidemiology at West Virginia University School of Public Health, and a clinical associate professor at the Center for the Study of Complementary and Alternative Therapies.

出版信息

Altern Complement Ther. 2013 Jun;19(3):139-146. doi: 10.1089/act.2013.19302. Epub 2013 Jun 18.

DOI:10.1089/act.2013.19302

PMID:26549967

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4634666/

Abstract

OBJECTIVE

The aim of this study was to investigate changes in knee pain, function, and related indices in older adults with osteoarthritis (OA) of the knee, following an 8-week meditation program.

METHODS

Eleven community-dwelling adults with physician- confirmed knee OA were enrolled in the study. Core outcomes included recommended measures of knee pain (Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC] and 11-point numeric rating scale [NRS]), function (WOMAC), and perceived global status (patient global assessment). Additional outcomes included: perceived stress; stress hardiness; mood; sleep; and sympathetic activation. Following baseline assessment, participants were trained briefly in mantra meditation and instructed to meditate for 15-20 minutes twice daily for 8 weeks, and to record each practice session on a daily log. Changes over time were analyzed using paired -tests.

RESULTS

Nine participants (82%) completed the study. Participants had statistically significant improvements in all core outcomes: knee pain (WOMAC: 47.7% ± 25.1% reduction, = 0.001; NRS: 42.6% ± 34.6% reduction, < 0.01); function (44.8% ± 29.9, = 0.001); and global status (45.7% ± 36.5, = 0.01); as well as knee stiffness ( = 0.005), mood ( = 0.05), and a WOMAC proxy for sleep disturbance ( = 0.005).

CONCLUSIONS

Findings from this pilot study suggest that a mantra meditation program may help reduce knee pain and dysfunction, as well as improving mood and related outcomes in adults with knee OA.

摘要

目的

本研究旨在调查患有膝关节骨关节炎（OA）的老年人在进行为期8周的冥想计划后，膝关节疼痛、功能及相关指标的变化。

方法

11名经医生确诊患有膝关节OA的社区居住成年人参与了本研究。核心结局指标包括推荐的膝关节疼痛测量指标（西安大略和麦克马斯特大学骨关节炎指数[WOMAC]和11点数字评定量表[NRS]）、功能（WOMAC）以及总体状况感知（患者总体评估）。其他结局指标包括：感知压力；心理韧性；情绪；睡眠；以及交感神经激活。在基线评估后，参与者接受了简短的曼陀罗冥想训练，并被要求每天冥想两次，每次15 - 20分钟，持续8周，并在每日日志中记录每次练习情况。使用配对t检验分析随时间的变化。

结果

9名参与者（82%）完成了研究。参与者在所有核心结局指标上均有统计学显著改善：膝关节疼痛（WOMAC：降低47.7%±25.1%，P = 0.001；NRS：降低42.6%±34.6%，P < 0.01）；功能（降低44.8%±29.9，P = 0.001）；以及总体状况（降低45.7%±36.5，P = 0.01）；还有膝关节僵硬（P = 0.005）、情绪（P = 0.05）以及WOMAC中睡眠障碍指标（P = 0.005）。