Coe J E
Proc Natl Acad Sci U S A. 1977 Feb;74(2):730-3. doi: 10.1073/pnas.74.2.730.
Normal Syrian hamster females contain a serum protein not found by simple gel diffusion assay in normal adult males. This sex-limited protein was called female protein (FP). Low levels of FP were found in sera from normal weanling male hamsters. Adult male hamsters castrated or treated with diethylstilbestrol also developed serum FP, which could be suppressed by administration of testosterone. Exogenous testosterone also suppressed serum FP in adult females, and ovarian function did not appear to be critical for maintenance of serum FP. Although FP is present in significant amounts (1-2 mg/ml) in adult females, its function is presently unknown.
正常叙利亚仓鼠雌性体内含有一种血清蛋白，正常成年雄性仓鼠通过简单的凝胶扩散试验无法检测到这种蛋白。这种性别限制蛋白被称为雌性蛋白（FP）。在正常断奶雄性仓鼠的血清中发现了低水平的FP。成年雄性仓鼠阉割或用己烯雌酚处理后也会产生血清FP，而睾酮的给药可以抑制这种蛋白。外源性睾酮也能抑制成年雌性仓鼠的血清FP，而且卵巢功能似乎对维持血清FP并不关键。尽管成年雌性仓鼠体内的FP含量很高（1-2毫克/毫升），但其功能目前尚不清楚。
