a Natural Product Chemistry and Process Development Division, CSIR-Institute of Himalayan Bioresource Technology , Palampur , India.
Crit Rev Anal Chem. 2016 Sep 2;46(5):400-12. doi: 10.1080/10408347.2015.1106932. Epub 2015 Nov 17.
NMR spectroscopy has multidisciplinary applications, including excellent impact in metabolomics. The analytical capacity of NMR spectroscopy provides information for easy qualitative and quantitative assessment of both endogenous and exogenous metabolites present in biological samples. The complexity of a particular metabolite and its contribution in a biological system are critically important for understanding the functional state that governs the organism's phenotypes. This review covers historical aspects of developments in the NMR field, its applications in chemical profiling, metabolomics, and quality control of plants and their derived medicines, foods, and other products. The bottlenecks of NMR in metabolic profiling are also discussed, keeping in view the future scope and further technological interventions.
NMR 光谱学具有多学科的应用，包括在代谢组学方面的出色影响。NMR 光谱学的分析能力为生物样品中内源性和外源性代谢物的定性和定量评估提供了信息。特定代谢物的复杂性及其在生物系统中的贡献对于理解控制生物体表型的功能状态至关重要。本文综述了 NMR 领域的发展历史，及其在化学剖析、代谢组学以及植物及其衍生药物、食品和其他产品的质量控制中的应用。还讨论了 NMR 在代谢物分析中的瓶颈问题，同时考虑了未来的发展前景和进一步的技术干预措施。
