Gajria Kavita, Kosinski Mark, Sikirica Vanja, Huss Michael, Livote Elayne, Reilly Kathleen, Dittmann Ralf W, Erder M Haim
Shire, 725 Chesterbrook Boulevard, Wayne, PA, 19087, USA.
QualityMetric Incorporated, 24 Albion Road, Building 400, Lincoln, RI, 02865, USA.
Health Qual Life Outcomes. 2015 Nov 17;13:184. doi: 10.1186/s12955-015-0379-1.
Measurement properties of the Weiss Functional Impairment Rating Scale-Parent Report Form (WFIRS-P), which assesses attention-deficit/hyperactivity disorder (ADHD)-related functional impairment in children/adolescents (6-17 years), were examined.
Data from seven randomized, controlled trials were pooled. Analyses were conducted in two random half-samples. WFIRS-P conceptual framework was evaluated using confirmatory factor analyses (CFA). Reliability was estimated using internal consistency (Cronbach's alpha) and test-retest reliability methods. Convergent validity was assessed using correlations between WFIRS-P domain scores and the ADHD-RS-IV and Clinical Global Impression-Severity (CGI-S) scales. Responsiveness was tested by comparing mean changes in WFIRS-P domain scores between responders and non-responders based on clinical criteria.
CFA adequately confirmed the item-to-scale relationships defined in the WFIRS-P conceptual framework. Cronbach's alpha coefficient exceeded 0.7 for all domains and test-retest reliability exceeded 0.7 for all but Risky Activities. With few exceptions, WFIRS-P domains correlated significantly (p < 0.05) with ADHD-RS-IV Total, Inattention and Hyperactivity-Impulsivity scores and CGI-S at baseline and follow-up in both random half-samples. Mean changes in WFIRS-P domain scores differed significantly between responder and non-responder groups in the expected direction (p < 0.001).
Study results support the reliability, validity and responsiveness of the WFIRS-P. Findings were replicated between two random samples, further demonstrating the robustness of results.
对Weiss功能损害评定量表家长报告表(WFIRS-P)的测量属性进行了检验,该量表用于评估儿童/青少年(6 - 17岁)与注意力缺陷多动障碍(ADHD)相关的功能损害。
汇总了七项随机对照试验的数据。在两个随机的半样本中进行分析。使用验证性因子分析(CFA)评估WFIRS-P概念框架。使用内部一致性(Cronbach's α)和重测信度方法估计信度。通过比较WFIRS-P领域得分与ADHD-RS-IV和临床总体印象严重程度(CGI-S)量表之间的相关性来评估收敛效度。根据临床标准,通过比较反应者和无反应者之间WFIRS-P领域得分的平均变化来测试反应性。
CFA充分证实了WFIRS-P概念框架中定义的项目与量表的关系。所有领域的Cronbach's α系数均超过0.7,除“危险活动”外,所有领域的重测信度均超过0.7。在两个随机半样本的基线和随访中,除少数例外,WFIRS-P领域与ADHD-RS-IV总分、注意力不集中和多动冲动得分以及CGI-S均有显著相关性(p < 0.05)。反应者和无反应者组之间WFIRS-P领域得分的平均变化在预期方向上有显著差异(p < 0.001)。
研究结果支持WFIRS-P的信度、效度和反应性。结果在两个随机样本中得到重复,进一步证明了结果的稳健性。