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2
Intravenous iron for the treatment of fatigue in nonanemic, premenopausal women with low serum ferritin concentration.静脉铁剂治疗低血清铁蛋白浓度的非贫血、绝经前女性的疲劳。
Blood. 2011 Sep 22;118(12):3222-7. doi: 10.1182/blood-2011-04-346304. Epub 2011 Jun 24.
3
Diagnosis and treatment of iron-deficiency anaemia during pregnancy and postpartum.妊娠期和产后缺铁性贫血的诊断与治疗。
Arch Gynecol Obstet. 2010 Nov;282(5):577-80. doi: 10.1007/s00404-010-1532-z. Epub 2010 Jun 25.
4
Efficacy and safety of intravenous iron therapy as an alternative/adjunct to allogeneic blood transfusion.静脉铁剂治疗作为异体输血替代/辅助治疗的疗效与安全性。
Vox Sang. 2008 Apr;94(3):172-183. doi: 10.1111/j.1423-0410.2007.01014.x. Epub 2007 Dec 7.
5
Micronutrient requirements of physically active women: what can we learn from iron?体育活动女性的微量营养素需求:我们能从铁元素中学到什么?
Am J Clin Nutr. 2005 May;81(5):1246S-1251S. doi: 10.1093/ajcn/81.5.1246.
6
Dietary Reference Intakes: development and uses for assessment of micronutrient status of women--a global perspective.膳食参考摄入量:从全球视角看其在评估女性微量营养素状况方面的制定与应用
Am J Clin Nutr. 2005 May;81(5):1194S-1197S. doi: 10.1093/ajcn/81.5.1194.
7
Iron supplementation for unexplained fatigue in non-anaemic women: double blind randomised placebo controlled trial.非贫血女性不明原因疲劳的铁补充剂治疗:双盲随机安慰剂对照试验
BMJ. 2003 May 24;326(7399):1124. doi: 10.1136/bmj.326.7399.1124.
8
Iron deficiency in Europe.欧洲的缺铁情况。
Public Health Nutr. 2001 Apr;4(2B):537-45. doi: 10.1079/phn2001139.
9
Reconsidering menorrhagia in gynecological practice. Is a 30-year-old definition still valid?重新审视妇科临床中的月经过多。一个30年之久的定义是否仍然有效?
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10
Menstrual blood loss and hematologic indices in healthy Chinese women.健康中国女性的月经失血情况及血液学指标
J Reprod Med. 1987 Nov;32(11):822-6.

女性缺铁的治疗。

Treatment of Iron Deficiency in Women.

作者信息

Breymann C, Römer T, Dudenhausen J W

机构信息

Forschung, Geburtshilfe, Universitätsspital Zürich.

Gyn/Gebh., Evang. Krankenhaus Köln-Weyertal.

出版信息

Geburtshilfe Frauenheilkd. 2013 Mar;73(3):256-261. doi: 10.1055/s-0032-1328271.

DOI:10.1055/s-0032-1328271
PMID:26633902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4647225/
Abstract

Iron deficiency with and without anaemia is a common cause of morbidity, particularly in women. Iron deficiency is generally the result of an imbalance between iron loss and iron absorption. In women with symptoms suspicious for iron deficiency, it is important to confirm or exclude the suspicion using proper tests. The use of serum ferritin levels is considered the gold standard for diagnosis. Although the ideal ferritin levels are not unknown the current consent is that levels < 40 ng/ml indicate iron deficiency, which needs to be treated in symptomatic patients. However, symptoms can already occur at ferritin levels of < 100 ng/ml and treatment must be adapted to the individual patient. Iron supplementation is only indicated in symptomatic patients diagnosed with iron deficiency whose quality of life is affected. It is important to treat iron deficiency together with its causes or risk factors. For example, blood loss from hypermenorrhea should be reduced. Women also need to receive information about the benefits of an iron-rich diet. If oral treatment with iron supplements is ineffective, parenteral iron administration is recommended.

摘要

缺铁伴或不伴贫血是发病的常见原因,尤其在女性中。缺铁通常是铁丢失与铁吸收失衡的结果。对于有缺铁可疑症状的女性,使用适当的检查来确认或排除这种怀疑很重要。血清铁蛋白水平的测定被认为是诊断的金标准。尽管理想的铁蛋白水平并非未知,但目前的共识是,铁蛋白水平<40 ng/ml表明缺铁,有症状的患者需要进行治疗。然而,在铁蛋白水平<100 ng/ml时症状就可能已经出现,治疗必须根据个体患者进行调整。铁补充剂仅适用于被诊断为缺铁且生活质量受到影响的有症状患者。治疗缺铁及其病因或危险因素很重要。例如,应减少月经过多导致的失血。女性还需要了解富含铁的饮食的益处。如果口服铁补充剂治疗无效,建议进行胃肠外铁剂给药。