Sieljacks Peter, Matzon Andreas, Wernbom Mathias, Ringgaard Steffen, Vissing Kristian, Overgaard Kristian
Section of Sport Science, Department of Public Health, Aarhus University, Dalgas Avenue 4, 8000, Århus, Denmark.
Department of Food and Nutrition and Sport Science, Center for Health and Performance, University of Gothenburg, Göteborg, Sweden.
Eur J Appl Physiol. 2016 Mar;116(3):513-25. doi: 10.1007/s00421-015-3304-8. Epub 2015 Dec 8.
Blood-flow restricted resistance exercise training (BFRE) is suggested to be effective in rehabilitation training, but more knowledge is required about its potential muscle damaging effects. Therefore, we investigated muscle-damaging effects of BFRE performed to failure and possible protective effects of previous bouts of BFRE or maximal eccentric exercise (ECC).
Seventeen healthy young men were allocated into two groups completing two exercise bouts separated by 14 days. One group performed BFRE in both exercise bouts (BB). The other group performed ECC in the first and BFRE in the second bout. BFRE was performed to failure. Indicators of muscle damage were evaluated before and after exercise.
The first bout in the BB group led to decrements in maximum isometric torque, and increases in muscle soreness, muscle water retention, and serum muscle protein concentrations after exercise. These changes were comparable in magnitude and time course to what was observed after first bout ECC. An attenuated response was observed in the repeated exercise bout in both groups.
We conclude that unaccustomed single-bout BFRE performed to failure induces significant muscle damage. Additionally, both ECC and BFRE can precondition against muscle damage induced by a subsequent bout of BFRE.
血流限制抗阻训练（BFRE）被认为在康复训练中有效，但对于其潜在的肌肉损伤作用仍需更多了解。因此，我们研究了进行至力竭的BFRE的肌肉损伤作用以及先前的BFRE或最大离心运动（ECC）可能的保护作用。
17名健康年轻男性被分为两组，完成两次间隔14天的运动 bout。一组在两次运动bout中均进行BFRE（BB组）。另一组在第一次运动bout中进行ECC，在第二次运动bout中进行BFRE。BFRE进行至力竭。在运动前后评估肌肉损伤指标。
BB组的第一次运动bout导致最大等长扭矩下降，运动后肌肉酸痛、肌肉水分潴留和血清肌肉蛋白浓度增加。这些变化在幅度和时间进程上与第一次运动bout ECC后观察到的情况相当。两组在重复运动bout中均观察到反应减弱。
我们得出结论，不习惯的单次进行至力竭的BFRE会导致明显的肌肉损伤。此外，ECC和BFRE均可对随后一次BFRE引起的肌肉损伤产生预处理作用。
