正常亚洲人群中泪液蕨类结晶模式与非侵入性泪膜破裂时间的关系
The Relationship Between Tear Ferning Patterns and Non-invasive Tear Break-up Time in Normal Asian Population.
作者信息
Ho Chien Yee, Mutalib Haliza Abdul, Ghazali Ahmad Rohi
机构信息
National University of Malaysia, Kuala Lumpur, Malaysia.
Universiti Kebangsaan Malaysia, Malaysia.
出版信息
J Optom. 2016 Jul-Sep;9(3):175-81. doi: 10.1016/j.optom.2015.10.004. Epub 2015 Dec 1.
PURPOSE
To investigate the relationship between tear ferning patterns (TFP) and non-invasive tear break-up time (NIBUT) in normal Asian subjects.
METHODS
One hundred and forty-five adults with no ocular surface disorders were recruited. TFP and NIBUT were determined. Tears were collected using a capillary tube and allowed to air dry at room temperature for 10min. TFP was later observed using a light microscope and classified according to Rolando's classification. Measurement for NIBUT was obtained using a Tearscope with the slit lamp magnification.
RESULTS
It was found that there is no significant difference between gender in TFP (Z=-1.77, P>.05) and NIBUT (Z=-1.475, P>.05). There is also no significant difference between Malay, Chinese, Indian, and other races in TFP, (H(3)=4.85, P>.05) and NIBUT (H(3)=2.18, P>.05). However, there is a significant difference between age groups of 20-29, 30-39, 40-49,and 50-60 years old in both TFP (H(3)=28.25, P<.01) and NIBUT (H(3)=36.50, P<.001). Spearman's correlation showed there was a significant relationship between TFP and NIBUT (r=-0.55, P<.001), age and NIBUT (r=-0.50, P<.001), age and TFP (r=0.41, P<.001), McMonnies score and NIBUT (r=-0.40, P<.001), McMonnies score and TFP (r=0.31, P<.001), as well as age and McMonnies score (r=0.52, P<.001).
CONCLUSION
TFP and NIBUT was age dependent but not gender and race dependent. Older subjects had higher grade of TFP and McMonnies questionnaire score but lower NIBUT value. TFP and NIBUT can be used to assess the tear film quality.
目的
研究正常亚洲受试者泪液蕨样变模式（TFP）与非侵入性泪膜破裂时间（NIBUT）之间的关系。
方法
招募了145名无眼表疾病的成年人。测定TFP和NIBUT。使用毛细管收集眼泪，并在室温下自然干燥10分钟。随后用光学显微镜观察TFP，并根据罗兰多分类法进行分类。使用带裂隙灯放大功能的泪膜镜测量NIBUT。
结果
发现TFP（Z=-1.77，P>0.05）和NIBUT（Z=-1.475，P>0.05）在性别之间无显著差异。TFP（H(3)=4.85，P>0.05）和NIBUT（H(3)=2.18，P>0.05）在马来族、华族、印度族和其他种族之间也无显著差异。然而，在20 - 29岁、30 - 39岁、40 - 49岁和50 - 60岁年龄组之间，TFP（H(3)=28.25，P<0.01）和NIBUT（H(3)=36.50，P<0.001）均存在显著差异。Spearman相关性分析显示，TFP与NIBUT之间存在显著关系（r=-0.55，P<0.001），年龄与NIBUT之间（r=-0.50，P<0.001），年龄与TFP之间（r=0.41，P<0.001），McMonnies评分与NIBUT之间（r=-0.40，P<0.001），McMonnies评分与TFP之间（r=0.31，P<0.001），以及年龄与McMonnies评分之间（r=0.52，P<0.001）。
结论
TFP和NIBUT与年龄相关，但与性别和种族无关。年龄较大的受试者TFP分级和McMonnies问卷评分较高，但NIBUT值较低。TFP和NIBUT可用于评估泪膜质量。
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