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乘车时间与心血管代谢风险标志物的不良关联。

Adverse associations of car time with markers of cardio-metabolic risk.

作者信息

Sugiyama Takemi, Wijndaele Katrien, Koohsari Mohammad Javad, Tanamas Stephanie K, Dunstan David W, Owen Neville

机构信息

Centre for Design Innovation, Faculty of Health Arts & Design, Swinburne University of Technology, Melbourne, VIC, Australia; School of Population Health, University of South Australia, Adelaide, SA, Australia; Baker IDI Heart and Diabetes Institute, Melbourne, VIC, Australia; Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.

MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom.

出版信息

Prev Med. 2016 Feb;83:26-30. doi: 10.1016/j.ypmed.2015.11.029. Epub 2015 Dec 4.

Abstract

OBJECTIVE

To examine associations of time spent sitting in cars with markers of cardio-metabolic risk in Australian adults.

METHOD

Data were from 2800 participants (age range: 34-65) in the 2011-12 Australian Diabetes, Obesity and Lifestyle Study. Self-reported time spent in cars was categorized into four groups: ≤15min/day; >15 to ≤30min/day; >30 to ≤60min/day; and >60min/day. Markers of cardio-metabolic risk were body mass index (BMI), waist circumference, systolic and diastolic blood pressure, triglycerides, HDL (high-density lipoprotein)-cholesterol, fasting plasma glucose, 2-h plasma glucose, a clustered cardio-metabolic risk score, and having the metabolic syndrome or not. Multilevel linear and logistic regression analyses examined associations of car time with each cardio-metabolic risk outcome, adjusting for socio-demographic and behavioral variables and medication use for blood pressure and cholesterol/triglycerides.

RESULTS

Compared to spending 15min/day or less in cars, spending more than 1h/day in cars was significantly associated with higher BMI, waist circumference, fasting plasma glucose, and clustered cardio-metabolic risk, after adjusting for socio-demographic attributes and potentially relevant behaviors including leisure-time physical activity and dietary intake. Gender interactions showed car time to be associated with higher BMI in men only.

CONCLUSIONS

Prolonged time spent sitting in cars, in particular over 1h/day, was associated with higher total and central adiposity and a more-adverse cardio-metabolic risk profile. Further studies, ideally using objective measures of sitting time in cars and prospective designs, are needed to confirm the impact of car use on cardio-metabolic disease risk.

摘要

目的

研究澳大利亚成年人在汽车中久坐时间与心血管代谢风险标志物之间的关联。

方法

数据来自2011 - 12年澳大利亚糖尿病、肥胖与生活方式研究中的2800名参与者(年龄范围:34 - 65岁)。自我报告的在汽车中度过的时间被分为四组:≤15分钟/天;>15至≤30分钟/天;>30至≤60分钟/天;以及>60分钟/天。心血管代谢风险标志物包括体重指数(BMI)、腰围、收缩压和舒张压、甘油三酯、高密度脂蛋白(HDL)胆固醇、空腹血糖、2小时血糖、综合心血管代谢风险评分以及是否患有代谢综合征。多水平线性和逻辑回归分析研究了乘车时间与每种心血管代谢风险结果之间的关联,并对社会人口统计学和行为变量以及用于血压和胆固醇/甘油三酯的药物使用情况进行了调整。

结果

在对社会人口统计学特征以及包括休闲时间身体活动和饮食摄入等潜在相关行为进行调整后,与每天在汽车中花费15分钟或更少时间相比,每天在汽车中花费超过1小时与更高的BMI、腰围、空腹血糖和综合心血管代谢风险显著相关。性别交互作用表明,乘车时间仅与男性较高的BMI相关。

结论

长时间坐在汽车中,尤其是每天超过1小时,与更高的全身和中心性肥胖以及更不利的心血管代谢风险状况相关。需要进一步的研究,理想情况下使用客观测量的乘车时间和前瞻性设计,以确认乘车对心血管代谢疾病风险的影响。

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