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评估用于检测1型人类免疫缺陷病毒抗体的滤纸上采集的血液。

Evaluation of blood collected on filter paper for detection of antibodies to human immunodeficiency virus type 1.

作者信息

Fortes P, Menitove J, Ross A, Steece R, Cabrian K, Ferrera C, Perkins P A, Sturge J, Lealos R, Krieger M S

机构信息

Gulf Coast Regional Blood Center, Houston, Texas 77504.

出版信息

J Clin Microbiol. 1989 Jun;27(6):1380-1. doi: 10.1128/jcm.27.6.1380-1381.1989.

DOI:10.1128/jcm.27.6.1380-1381.1989
PMID:2666445
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC267562/
Abstract

This study was undertaken to evaluate the sensitivity and specificity of a commercial enzyme immunoassay in detecting antibody to human immunodeficiency virus type 1 using whole-blood specimens collected onto filter paper. Results obtained with specimens collected onto filter paper were comparable with those obtained with the corresponding serum or plasma specimens.

摘要

本研究旨在评估一种商用酶免疫测定法在检测滤纸上采集的全血标本中抗1型人类免疫缺陷病毒抗体时的敏感性和特异性。滤纸上采集的标本所获得的结果与相应血清或血浆标本所获得的结果相当。

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What a drop can do: dried blood spots as a minimally invasive method for integrating biomarkers into population-based research.一滴血能发挥怎样的作用：干血斑作为一种将生物标志物纳入基于人群研究的微创方法。
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本文引用的文献

1
An enzyme-linked immunosorbent assay for thyroxine in dried blood spotted on filter paper.用于检测滤纸上干血斑中甲状腺素的酶联免疫吸附测定法。
J Immunol Methods. 1985 Sep 3;82(1):83-9. doi: 10.1016/0022-1759(85)90227-3.
2
Markers of hepatitis viruses A and B: direct comparison between whole serum and blood spotted on filter-paper.甲型和乙型肝炎病毒标志物：全血清与滤纸上血斑的直接比较
Bull World Health Organ. 1985;63(5):935-9.
3
A prevalence study of HIV antibodies in rural Kenya.肯尼亚农村地区艾滋病毒抗体流行情况研究。
Scand J Infect Dis. 1987;19(4):395-401. doi: 10.3109/00365548709021671.
4
Whole blood collection on filter paper is an effective means of obtaining samples for human immunodeficiency virus antibody assay.
AIDS Res Hum Retroviruses. 1988 Apr;4(2):131-6. doi: 10.1089/aid.1988.4.131.
5
Seroprevalence of human immunodeficiency virus among childbearing women. Estimation by testing samples of blood from newborns.育龄妇女中人类免疫缺陷病毒的血清流行率。通过检测新生儿血样进行估计。
N Engl J Med. 1988 Mar 3;318(9):525-30. doi: 10.1056/NEJM198803033180901.