Feng Yesu, Gordon Jeremy W, Shin Peter J, von Morze Cornelius, Lustig Michael, Larson Peder E Z, Ohliger Michael A, Carvajal Lucas, Tropp James, Pauly John M, Vigneron Daniel B
Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA, USA.
Department of Electrical Engineering and Computer Sciences, UC Berkeley, Berkeley, CA, USA.
J Magn Reson. 2016 Jan;262:1-7. doi: 10.1016/j.jmr.2015.10.018. Epub 2015 Oct 31.
A calibrationless parallel imaging technique developed previously for (1)H MRI was modified and tested for hyperpolarized (13)C MRI for applications requiring large FOV and high spatial resolution. The technique was demonstrated with both retrospective and prospective under-sampled data acquired in phantom and in vivo rat studies. A 2-fold acceleration was achieved using a 2D symmetric EPI readout equipped with random blips on the phase encode dimension. Reconstructed images showed excellent qualitative agreement with fully sampled data. Further acceleration can be achieved using acquisition schemes that incorporate multi-dimensional under-sampling.
一种先前为氢质子磁共振成像（¹H MRI）开发的无校准并行成像技术经过修改，并针对需要大视野和高空间分辨率的应用，对超极化碳-13磁共振成像（¹³C MRI）进行了测试。该技术通过在体模和体内大鼠研究中采集的回顾性和前瞻性欠采样数据得到了验证。在相位编码维度上配备随机脉冲的二维对称回波平面成像（EPI）读出方式实现了2倍加速。重建图像与全采样数据在定性上具有出色的一致性。使用包含多维欠采样的采集方案可实现进一步加速。
