羟氯喹诱导的急性泛发性脓疱性皮疹伴斑贴试验阳性
Hydroxychloroquine-induced acute generalized exanthematous pustulosis with positive patch-testing.
作者信息
Charfi Ons, Kastalli Sarrah, Sahnoun Rym, Lakhoua Ghozlane
机构信息
Department of Pharmacology, National Center of Pharmacovigilance, 9 Avenue du Dr Zouhaier Essafi 1006, Tunis, Tunisia.
Department of Pharmacology, National Center of Pharmacovigilance, 9 Avenue du Dr Zouhaier Essafi 1006, Tunis, Tunisia; Department of Pharmacology, Tunis El Manar University, Faculty of Medicine, 15 Rue Djebel Lakhdhar, La Rabta, 1007, Tunis, Tunisia.
出版信息
Indian J Pharmacol. 2015 Nov-Dec;47(6):693-4. doi: 10.4103/0253-7613.169589.
Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse reaction, mostly induced by drugs. Hydroxychloroquine have been rarely reported in literature as a causative drug of this reaction. We report a case of AGEP induced by hydroxychloroquine with systemic involvement and confirmed by positive patch testing.
急性泛发性脓疱性皮病（AGEP）是一种严重的皮肤不良反应，大多由药物引起。文献中很少有关于羟氯喹作为该反应致病药物的报道。我们报告一例由羟氯喹引起的伴有全身症状的AGEP病例，斑贴试验阳性证实了诊断。
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