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经皮伤口氧疗对压疮愈合的影响：一项单盲多中心随机对照试验

Transdermal Wound Oxygen Therapy on Pressure Ulcer Healing: A Single-Blind Multi-Center Randomized Controlled Trial.

作者信息

Azimian Jalil, Dehghan Nayeri Nahid, Pourkhaleghi Enis, Ansari Monireh

机构信息

Nursing and Midwifery Faculty, School of Nursing and Midwifery, Qazvin University of Medical Sciences, Qazvin, IR Iran; Nursing and Midwifery Faculty, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, IR Iran.

Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, IR Iran.

出版信息

Iran Red Crescent Med J. 2015 Nov 3;17(11):e20211. doi: 10.5812/ircmj.20211. eCollection 2015 Nov.

DOI:10.5812/ircmj.20211
PMID:26734476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4698133/
Abstract

BACKGROUND

Although healthcare quality has considerably improved in many countries, pressure ulcer is still a major health challenge worldwide.

OBJECTIVES

The current study aimed to evaluate the effects of TWOT on the healing of pressure ulcers.

PATIENTS AND METHODS

This study was a randomized controlled trial, and the convenient sample including 100 patients hospitalized in two university-affiliated medical-surgical intensive care units and one neurology unit located in Qazvin, Iran were studied. Patients with stage II-IV pressure ulcer on the sacral or ischial areas were randomly assigned to either the control or the experimental groups. The experimental group received a 12-day transdermal wound oxygen therapy. Wound status was assessed seven times before the intervention, as well as two, four, six, eight, ten, and twelve days after the intervention.

RESULTS

After 12 days of wound oxygen therapy, the number of patients with complete wound healing in the experimental group was significantly greater than that of the control group. Moreover, the total mean of wound area in the experimental group was significantly lower than that of the control group.

CONCLUSIONS

Transdermal wound oxygen therapy can effectively promote wound healing in patients with pressure ulcers.

摘要

背景

尽管许多国家的医疗质量有了显著提高，但压疮仍是全球主要的健康挑战。

目的

本研究旨在评估经皮伤口氧疗法（TWOT）对压疮愈合的影响。

患者与方法

本研究为随机对照试验，对伊朗加兹温市两所大学附属医院的外科重症监护病房和一个神经科病房收治的100例患者进行了便利抽样研究。骶部或坐骨部位有II-IV期压疮的患者被随机分为对照组和试验组。试验组接受为期12天的经皮伤口氧疗。在干预前评估7次伤口状况，在干预后第2、4、6、8、10和12天各评估1次。

结果

伤口氧疗12天后，试验组伤口完全愈合的患者数量显著多于对照组。此外，试验组伤口面积的总均值显著低于对照组。

结论

经皮伤口氧疗可有效促进压疮患者的伤口愈合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb71/4698133/e633474bd831/ircmj-17-11-20211-i001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb71/4698133/e633474bd831/ircmj-17-11-20211-i001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb71/4698133/e633474bd831/ircmj-17-11-20211-i001.jpg

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Hyperbaric oxygen therapy for chronic wounds.慢性伤口的高压氧治疗
Cochrane Database Syst Rev. 2012 Apr 18(4):CD004123. doi: 10.1002/14651858.CD004123.pub3.
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Predictors of pressure ulcers in adult critical care patients.成人重症监护患者压疮的预测因素。
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Front Surg. 2022 Apr 13;9:739250. doi: 10.3389/fsurg.2022.739250. eCollection 2022.
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Optical Oxygen Sensor Patch Printed with Polystyrene Microparticles-based Ink on Flexible Substrate.基于聚苯乙烯微粒油墨在柔性基板上印刷的光学氧传感器贴片。
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Improving Self-Management Skills Among People With Spinal Cord Injury: Protocol for a Mixed-Methods Study.提高脊髓损伤患者的自我管理技能：一项混合方法研究的方案
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