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根据埃塞俄比亚西北部吉加地区正在进行的疟疾控制干预措施、社会人口和环境变量评估当前疟疾状况

Assessment of Current Malaria Status in Light of the Ongoing Control Interventions, Socio-Demographic and Environmental Variables in Jiga Area, Northwest Ethiopia.

作者信息

Ayalew Seble, Mamo Hassen, Animut Abebe, Erko Berhanu

机构信息

Department of Microbial, Cellular and Molecular Biology, College of Natural Sciences, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia.

Aklilu Lemma Institute of Pathobiology, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia.

出版信息

PLoS One. 2016 Jan 11;11(1):e0146214. doi: 10.1371/journal.pone.0146214. eCollection 2016.

Abstract

Following substantial decline in malaria burden in Ethiopia, the country is planning to eliminate malaria in certain low transmission settings by 2020. To evaluate the attainability of this goal in-depth examination of malaria parasite carriage at community level is necessary. This study was, therefore, aimed at assessing the current situation of malaria in relation to ongoing control interventions in Jiga area, Jabi Tehnan District in northwest Ethiopia. A cross-sectional household (HH) survey was conducted in November-December 2013. Out of 2,574 HHs (11,815 people) in the entire Jabi Tehnan District, 392 (accommodating 1911 people) were randomly selected from three purposely selected villages. One randomly selected member from each selected HH was tested for malaria using rapid diagnostic test (mRDT). All participants tested for malaria (n = 392) were afebrile (axillary temperature <37.5°C). Eleven individuals (2.8%, 95% confidence interval (CI):1.2-4.4%) were found to be mRDT positive. Most HHs (95.9%, 95% CI: 93.5-97.5%) had at least 1 long-lasting insecticidal net (LLIN). Insecticide residual spraying (IRS) coverage the last six months was 85.5% (95% CI: 82.0-88.9%). Malaria prevalence remains unexpectedly high despite high HH coverage of control interventions.

摘要

在埃塞俄比亚疟疾负担大幅下降之后,该国计划到2020年在某些低传播地区消除疟疾。为评估这一目标的可实现性,有必要在社区层面深入检查疟原虫携带情况。因此,本研究旨在评估埃塞俄比亚西北部贾比·特南地区吉加 area 正在进行的控制干预措施相关的疟疾现状。2013年11月至12月进行了一项横断面家庭(HH)调查。在贾比·特南地区的2574户家庭(11815人)中,从三个特意挑选的村庄中随机选取了392户(容纳1911人)。从每个选定的家庭中随机选取一名成员,使用快速诊断测试(mRDT)检测疟疾。所有接受疟疾检测的参与者(n = 392)均无发热(腋温<37.5°C)。发现11人(2.8%,95%置信区间(CI):1.2 - 4.4%)mRDT呈阳性。大多数家庭(95.9%,95%CI:93.5 - 97.5%)至少有一顶长效驱虫蚊帐(LLIN)。过去六个月的杀虫剂残留喷洒(IRS)覆盖率为85.5%(95%CI:82.0 - 88.9%)。尽管家庭对控制干预措施的覆盖率很高,但疟疾患病率仍然出乎意料地高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/284e/4709195/9920119371b8/pone.0146214.g001.jpg

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