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连续股神经阻滞对全膝关节置换术后患者膝关节功能及生活质量的影响。

Influences of continuous femoral nerve block on knee function and quality of life in patients following total knee arthroplasty.

作者信息

Wang Fen, Zhou Yingjie, Sun Jiajun, Yang Chunxi

机构信息

Department of Anesthesiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.

Department of Orthopedics, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.

出版信息

Int J Clin Exp Med. 2015 Oct 15;8(10):19120-5. eCollection 2015.

Abstract

OBJECTIVE

Continuous femoral nerve block (CFNB), guided by ultrasound combined nerve stimulations, offers advantages for both sides and provides effective postoperative analgesia after total knee arthroplasty (TKA). The objective of this study was to evaluate the medium-term impact of continuous femoral nerve block on knee function and quality of life in patients following TKA.

METHODS

This was a follow-up study. Total 168 adult patients scheduled for elective TKA were randomly allocated to receive postoperative continuous femoral nerve block guided by ultrasound combined nerve stimulator (group CFNB, n = 82) or patient-controlled epidural analgesia (group PCEA, n = 86). Quality of life, knee function, patient satisfaction, pain medication and associated adverse effects were compared at 1, 3, 6, and 12 months postoperatively. Quality of life was assessed using the Medical Outcomes Study Short Form-36 Health Survey (MOS SF-36), and clinical results were assessed using the Hospital for Special Surgery (HSS) Knee Scoring System. Patient satisfaction scores were divided into four categories.

RESULTS

A total of 162 patients completed the 12-month follow-up. The CFNB group patients had significantly improved SF-36 scores and physical function at 1 month postoperatively (P < 0.05); the remaining seven dimensions were similar between the two groups. No differences were observed at 3, 6 or 12 months. HSS scores for the four observational time points were comparable. The CFNB group patients reported less pain; improved knee function, maximum flexion and strength; less celecoxib consumption and fewer side effects at 1 month than the PCEA group patients. The satisfaction score at 12 months decreased significantly, compared with that at 1 month in both groups (3.6 to 2.95 and 3.4 to 2.45, respectively). No difference in satisfaction score was observed between the two groups.

CONCLUSIONS

Continuous femoral nerve block not only could provide effective postoperative analgesia but also could improve joint function and quality of life in patients at one month postoperatively. Continuous femoral nerve block is a good choice for postoperative analgesia after TKA.

摘要

目的

超声联合神经刺激引导下的连续股神经阻滞(CFNB)对双侧均具有优势,并能为全膝关节置换术(TKA)提供有效的术后镇痛。本研究的目的是评估连续股神经阻滞对TKA术后患者膝关节功能和生活质量的中期影响。

方法

这是一项随访研究。总共168例计划接受择期TKA的成年患者被随机分配,分别接受超声联合神经刺激器引导下的术后连续股神经阻滞(CFNB组,n = 82)或患者自控硬膜外镇痛(PCEA组,n = 86)。在术后1、3、6和12个月比较生活质量、膝关节功能、患者满意度、止痛药物使用情况及相关不良反应。使用医学结局研究简明健康调查(MOS SF-36)评估生活质量,使用特种外科医院(HSS)膝关节评分系统评估临床结果。患者满意度评分分为四类。

结果

共有162例患者完成了12个月的随访。CFNB组患者术后1个月时SF-36评分和身体功能显著改善(P < 0.05);其余七个维度在两组之间相似。在3、6或12个月时未观察到差异。四个观察时间点的HSS评分具有可比性。CFNB组患者在术后1个月时疼痛较轻;膝关节功能、最大屈曲度和力量有所改善;塞来昔布消耗量较少,副作用比PCEA组患者少。与两组术后1个月时相比,12个月时的满意度评分显著降低(分别从3.6降至2.95和从3.4降至2.45)。两组之间的满意度评分没有差异。

结论

连续股神经阻滞不仅可以提供有效的术后镇痛,还可以在术后1个月改善患者的关节功能和生活质量。连续股神经阻滞是TKA术后镇痛选择。

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