Ginjupalli Kishore, Alla Rama Krishna, Tellapragada Chaitanya, Gupta Lokendra, Upadhya Perampalli Nagaraja
Associate Professor, Department of Dental Materials, Manipal College of Dental Sciences, Manipal University, Manipal, India.
Assistant Professor, Department of Dental Materials, Vishnu Dental College, Bhimavaram, India.
J Prosthet Dent. 2016 Jun;115(6):722-8. doi: 10.1016/j.prosdent.2015.11.006. Epub 2016 Jan 13.
Conventional spray and the immersion disinfection of irreversible hydrocolloid impression materials may lead to dimensional changes.
The purpose of this in vitro study was to investigate the antimicrobial activity and properties of irreversible hydrocolloid impression materials incorporated with silver nanoparticles.
The antimicrobial activity and properties of 2 commercially available irreversible hydrocolloid impression materials were evaluated after incorporating varying concentrations of silver nanoparticles. Antimicrobial activity was determined using the disk diffusion method. The gel strength, permanent deformation, flow, and gelation time were measured according to American Dental Association specification #18. Analysis of variance was used to identify the significant differences within and across the groups (α=.05).
Adding silver nanoparticles to irreversible hydrocolloid impression materials resulted in superior antimicrobial activity without adversely affecting their properties. Adding silver nanoparticles to Zelgan significantly increased the gel strength compared with the control group, except at 5 wt%. However, the gel strength of Tropicalgin was unaffected except at 5 wt%. An increase in the permanent deformation was found with the incorporation of silver nanoparticles in both Zelgan and Tropicalgin. The flow of Zelgan increased with the incorporation of silver nanoparticles, whereas a decrease in the flow of Tropicalgin was observed at 1 wt% and 2 wt%. An increase in the gelation time of both Zelgan and Tropicalgin was observed with the incorporation of silver nanoparticles.
Based on this in vitro study, silver nanoparticles can be incorporated into irreversible hydrocolloid impression materials as antimicrobial agents without adversely affecting their properties.
传统的喷雾法和对不可逆水胶体印模材料进行浸泡消毒可能会导致尺寸变化。
本体外研究的目的是调查添加银纳米颗粒的不可逆水胶体印模材料的抗菌活性和性能。
在两种市售的不可逆水胶体印模材料中加入不同浓度的银纳米颗粒后,评估其抗菌活性和性能。采用纸片扩散法测定抗菌活性。根据美国牙科协会规范#18测量凝胶强度、永久变形、流动性和胶凝时间。采用方差分析确定组内和组间的显著差异(α = 0.05)。
向不可逆水胶体印模材料中添加银纳米颗粒可产生优异的抗菌活性,且不会对其性能产生不利影响。与对照组相比,向Zelgan中添加银纳米颗粒除了在5 wt%时外,显著提高了凝胶强度。然而,Tropicalgin的凝胶强度除了在5 wt%时外未受影响。在Zelgan和Tropicalgin中加入银纳米颗粒均导致永久变形增加。Zelgan的流动性随着银纳米颗粒的加入而增加,而Tropicalgin在1 wt%和2 wt%时观察到流动性下降。在Zelgan和Tropicalgin中加入银纳米颗粒均观察到胶凝时间增加。
基于本体外研究,银纳米颗粒可作为抗菌剂添加到不可逆水胶体印模材料中,而不会对其性能产生不利影响。