Sikdar Sohely, Papadopoulou Maria, Dubois Jacques
Laboratoire de Chimie Bioanalytique, Toxicologie et Chimie Physique Appliquée, Faculté de Pharmacie, Université Libre de Bruxelles (ULB), Brussels, Belgium.
J Cosmet Dermatol. 2016 Mar;15(1):72-7. doi: 10.1111/jocd.12176. Epub 2016 Jan 22.
Sulforaphane (SFN), a natural compound occurring in cruciferous vegetables, has been known for years as a chemopreventive agent against many types of cancer. Recently, it has been investigated as an antioxidant and anti-aging agent, and interesting conclusions have been made over the last decade. SFN demonstrated protective effects against ultraviolet (UV)-induced skin damage through several mechanisms of action, for example, decrease of reactive oxygen species production, inhibition of matrix metalloproteinase expression, and induction of phase 2 enzymes. SFN used as a protective agent against UV damage is a whole new matter, and it seems to be a very promising ingredient in upcoming anti-aging drugs and cosmetics.
萝卜硫素（SFN）是一种存在于十字花科蔬菜中的天然化合物，多年来一直作为预防多种癌症的化学预防剂为人所知。最近，它被作为一种抗氧化剂和抗衰老剂进行研究，并且在过去十年中得出了有趣的结论。萝卜硫素通过多种作用机制对紫外线（UV）诱导的皮肤损伤表现出保护作用，例如，减少活性氧的产生、抑制基质金属蛋白酶的表达以及诱导Ⅱ相酶。将萝卜硫素用作抗紫外线损伤的保护剂是一个全新的课题，并且它似乎是即将出现的抗衰老药物和化妆品中一种非常有前景的成分。
