Walter P
Klinik für Augenheilkunde, Uniklinik RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Deutschland.
Ophthalmologe. 2016 Feb;113(2):175-88; quiz 189. doi: 10.1007/s00347-015-0202-8.
Sensory neuroprostheses for restoration of vision are a technical approach for treatment of previously untreatable blindness. These systems consist of a technical sensor such as a camera and an implanted multi-electrode array within the visual system. The image information from the sensor is processed with specially designed integrated circuits in such a way that the stimulation pulses can be determined and presented to the implanted multi-electrode matrix. Energy supply and the transfer of the stimulus pulse information is realized either via direct cable connections within the site of the implant or by telemetric inductive links. Currently, two retinal implant systems are approved in the European Union (EU) to be used in blind patients with retinitis pigmentosa. With both systems basic visual functions can be restored. The complication rate is relatively low given the complexity of the surgical procedure. Other systems are still under development but approval studies by several manufacturers and consortia are already in preparation.
用于恢复视力的感觉神经假体是一种治疗以前无法治疗的失明的技术手段。这些系统由一个技术传感器(如摄像头)和视觉系统内植入的多电极阵列组成。来自传感器的图像信息通过专门设计的集成电路进行处理,以便确定刺激脉冲并将其呈现给植入的多电极矩阵。能量供应和刺激脉冲信息的传输可通过植入部位内的直接电缆连接或遥测感应链路来实现。目前,两种视网膜植入系统已在欧盟获批用于患有色素性视网膜炎的盲人患者。使用这两种系统都可以恢复基本视觉功能。鉴于手术过程的复杂性,并发症发生率相对较低。其他系统仍在开发中,但几家制造商和财团的批准研究已在筹备中。