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α和β1型干扰素信号传导：通向多样生物学结果的途径。

Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes.

作者信息

Ng Cherie T, Mendoza Juan L, Garcia K Christopher, Oldstone Michael B A

机构信息

Department of Immunology & Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Department of Molecular & Cellular Physiology and Department of Structural Biology, Howard Hughes Medical Institute, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA.

出版信息

Cell. 2016 Jan 28;164(3):349-52. doi: 10.1016/j.cell.2015.12.027.

DOI:10.1016/j.cell.2015.12.027
PMID:26824652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4733246/
Abstract

Type I interferon (IFN-I) elicits a complex cascade of events in response to microbial infection. Here, we review recent developments illuminating the large number of IFN-I species and describing their unique biologic functions.

摘要

I型干扰素（IFN-I）在应对微生物感染时引发一系列复杂的事件。在此，我们回顾了近期的研究进展，这些进展揭示了大量的I型干扰素种类，并描述了它们独特的生物学功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69d2/4733246/149dfae9c325/nihms746732f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69d2/4733246/149dfae9c325/nihms746732f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69d2/4733246/149dfae9c325/nihms746732f1.jpg

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