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激光烧结和加工植入物经可吸收喷砂介质处理后的表面表征及体内评估:一项在绵羊身上的研究

Surface characterization and in vivo evaluation of laser sintered and machined implants followed by resorbable-blasting media process: A study in sheep.

作者信息

Bowers Michelle, Yoo Daniel, Marin Charles, Gil Luiz, Shabaka Nour, Goldstein Matt, Janal Malvin, Tovar Nick, Hirata Ronaldo, Bonfante Estevam, Coelho Paulo

机构信息

345 E 24th Street, 10010, Biomaterials and Biomimetics, New York University, New York, NY, USA, rh1694@@nyu.edu.

出版信息

Med Oral Patol Oral Cir Bucal. 2016 Mar 1;21(2):e206-13. doi: 10.4317/medoral.20946.

DOI:10.4317/medoral.20946
PMID:26827064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4788801/
Abstract

BACKGROUND

This study aimed to compare the histomorphometric and histological bone response to laser-sintered implants followed by resorbable-blasting media (RBM) process relative to standard machined/RBM surface treated implants.

MATERIAL AND METHODS

Six male sheep (n=6) received 2 Ti-6Al-4V implants (1 per surface) in each side of the mandible for 6 weeks in vivo. The histomorphometric parameters bone-implant contact (BIC) and bone area fraction occupancy (BAFO) were evaluated.

RESULTS

Optical interferometry revealed higher Sa and Sq values for the laser-sintered/RBM surface in relation to standard/RBM implants. No significant differences in BIC were observed between the two groups (p>0.2), but significantly higher BAFO was observed for standard/RBM implants (p<0.01).

CONCLUSIONS

The present study demonstrated that both surfaces were biocompatible and osseoconductive, and the combination of laser sintering and RBM has no advantage over the standard machined implants with subsequent RBM.

摘要

背景

本研究旨在比较激光烧结种植体经可吸收喷砂介质(RBM)处理后与标准机械加工/RBM表面处理种植体的组织形态计量学和组织学骨反应。

材料与方法

六只雄性绵羊(n = 6),在下颌骨两侧各植入2枚Ti-6Al-4V种植体(每个表面1枚),体内植入6周。评估组织形态计量学参数骨-种植体接触(BIC)和骨面积分数占有率(BAFO)。

结果

光学干涉测量显示,与标准/RBM种植体相比,激光烧结/RBM表面的Sa和Sq值更高。两组之间的BIC未观察到显著差异(p>0.2),但标准/RBM种植体的BAFO显著更高(p<0.01)。

结论

本研究表明,两种表面均具有生物相容性和骨传导性,激光烧结与RBM的组合相对于后续进行RBM处理的标准机械加工种植体并无优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7fb/4788801/54eb8202bf0c/medoral-21-e206-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7fb/4788801/162e617da80d/medoral-21-e206-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7fb/4788801/f3fb6e6750fd/medoral-21-e206-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7fb/4788801/06b93d0d097b/medoral-21-e206-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7fb/4788801/54eb8202bf0c/medoral-21-e206-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7fb/4788801/162e617da80d/medoral-21-e206-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7fb/4788801/f3fb6e6750fd/medoral-21-e206-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7fb/4788801/06b93d0d097b/medoral-21-e206-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7fb/4788801/54eb8202bf0c/medoral-21-e206-g004.jpg

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