Cayrol Bastien, Delteil Amandine, Gobbato Enrico, Kroj Thomas, Morel Jean-Benoit
b INRA, UMR BGPI INRA/CIRAD/SupAgro, Campus International de Baillarguet , TA A 54/K, 34398 Montpellier , France.
a CIRAD, UMR BGPI INRA/CIRAD/SupAgro, Campus International de Baillarguet , TA A 54/K, 34398 Montpellier , France.
Plant Signal Behav. 2016;11(4):e1149676. doi: 10.1080/15592324.2016.1149676.
Receptor-like kinases (RLKs) play key roles in disease resistance, in particular basal immunity. They recognize patterns produced by the pathogen invasion and often work as complexes in the plasma membrane. Among these RLKs, there is increasing evidence in several plant species of the key role of Wall-associated kinases (WAKs) in disease resistance. We recently showed using rice (Oryza sativa) loss-of-function mutants of three transcriptionally co-regulated OsWAK genes that individual OsWAKs are positively required for quantitative resistance to the rice blast fungus, Magnaporthe oryzae. This finding was unexpected since WAK genes belong to large gene families where functional redundancy is expected. Here we provide evidence that this may be due to complex physical interaction between OsWAK proteins.
类受体激酶（RLKs）在抗病性尤其是基础免疫中发挥关键作用。它们识别病原体入侵产生的模式，并且常常在质膜中作为复合体发挥作用。在这些RLKs中，越来越多的证据表明，在几种植物物种中，细胞壁相关激酶（WAKs）在抗病性中起关键作用。我们最近利用三个转录共调控的OsWAK基因的水稻（Oryza sativa）功能缺失突变体表明，单个OsWAK对水稻稻瘟病菌Magnaporthe oryzae的定量抗性是正向必需的。这一发现出乎意料，因为WAK基因属于预期存在功能冗余的大基因家族。在这里，我们提供证据表明，这可能是由于OsWAK蛋白之间复杂的物理相互作用。
