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小麦壁相关类受体激酶TaWAK-6D介导对两种真菌病原体的广泛抗性。

The Wheat Wall-Associated Receptor-Like Kinase TaWAK-6D Mediates Broad Resistance to Two Fungal Pathogens and .

作者信息

Qi Haijun, Guo Feilong, Lv Liangjie, Zhu Xiuliang, Zhang Li, Yu Jinfeng, Wei Xuening, Zhang Zengyan

机构信息

The National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.

Institute of Cereal and Oil Crops, Hebei Academy of Agriculture and Forestry Sciences, Shijiazhuang, China.

出版信息

Front Plant Sci. 2021 Oct 27;12:758196. doi: 10.3389/fpls.2021.758196. eCollection 2021.

DOI:10.3389/fpls.2021.758196
PMID:34777437
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8579037/
Abstract

The soil-borne fungi and are the major pathogens for the economically important diseases crown rot (FCR) and sharp eyespot of common wheat (), respectively. However, there has been no report on the broad resistance of wheat genes against both and . In the current study, we identified , a wall-associated kinase (WAK) which is an encoding gene located on chromosome 6D, and demonstrated its broad resistance role in the wheat responses to both and infection. transcript induction by and was related to the resistance degree of wheat and the gene expression was significantly induced by exogenous pectin treatment. Silencing of compromised wheat resistance to and , and repressed the expression of a serial of wheat defense-related genes. Ectopic expression of in positively modulated the expression of several defense-related genes. TaWAK-6D protein was determined to localize to the plasma membrane in wheat and . Collectively, the TaWAK-6D at the plasma membrane mediated the broad resistance responses to both and in wheat at the seedling stage. This study, therefore, concludes that is a promising gene for improving wheat broad resistance to FCR and sharp eyespot.

摘要

土传真菌分别是经济上重要的小麦根腐病（FCR）和小麦纹枯病的主要病原菌。然而，尚未有关于小麦基因对这两种病原菌具有广谱抗性的报道。在本研究中，我们鉴定了一个位于6D染色体上的编码基因——壁相关激酶（WAK）TaWAK-6D，并证明了其在小麦对这两种病原菌感染的反应中具有广谱抗性作用。TaWAK-6D的转录诱导与小麦的抗性程度相关，并且外源果胶处理可显著诱导该基因表达。TaWAK-6D基因沉默会削弱小麦对这两种病原菌的抗性，并抑制一系列小麦防御相关基因的表达。TaWAK-6D在拟南芥中的异位表达正向调控了几个防御相关基因的表达。已确定TaWAK-6D蛋白定位于小麦和拟南芥的质膜上。总体而言，质膜上的TaWAK-6D介导了小麦幼苗期对这两种病原菌的广谱抗性反应。因此，本研究得出结论，TaWAK-6D是提高小麦对根腐病和纹枯病广谱抗性的一个有前景的基因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00c5/8579037/e22f486d3f86/fpls-12-758196-g0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00c5/8579037/57b6925a427f/fpls-12-758196-g0001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00c5/8579037/c96b4797d7e5/fpls-12-758196-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00c5/8579037/e22f486d3f86/fpls-12-758196-g0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00c5/8579037/57b6925a427f/fpls-12-758196-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00c5/8579037/7563a8e1a453/fpls-12-758196-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00c5/8579037/c0d7395bb8d2/fpls-12-758196-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00c5/8579037/83a280892b55/fpls-12-758196-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00c5/8579037/96bf00be4f22/fpls-12-758196-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00c5/8579037/3c0c4c159d74/fpls-12-758196-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00c5/8579037/c96b4797d7e5/fpls-12-758196-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00c5/8579037/e22f486d3f86/fpls-12-758196-g0008.jpg

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