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Heart failure: Ketone bodies as fuel in heart failure.

作者信息

Huynh Karina

出版信息

Nat Rev Cardiol. 2016 Mar;13(3):122-3. doi: 10.1038/nrcardio.2016.22. Epub 2016 Feb 11.

DOI:10.1038/nrcardio.2016.22

PMID:26864914

Abstract

摘要

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Metabolic remodeling of substrate utilization during heart failure progression.

Heart Fail Rev. 2019 Jan;24(1):143-154. doi: 10.1007/s10741-018-9713-0.

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本文引用的文献

The Failing Heart Relies on Ketone Bodies as a Fuel.

Circulation. 2016 Feb 23;133(8):698-705. doi: 10.1161/CIRCULATIONAHA.115.017355. Epub 2016 Jan 27.

Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure.

Circulation. 2016 Feb 23;133(8):706-16. doi: 10.1161/CIRCULATIONAHA.115.017545. Epub 2016 Jan 27.

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相似文献

Heart failure: Ketone bodies as fuel in heart failure.

Nat Rev Cardiol. 2016 Mar;13(3):122-3. doi: 10.1038/nrcardio.2016.22. Epub 2016 Feb 11.

Ketones Step to the Plate: A Game Changer for Metabolic Remodeling in Heart Failure?

Circulation. 2016 Feb 23;133(8):689-91. doi: 10.1161/CIRCULATIONAHA.116.021230. Epub 2016 Jan 27.

The Failing Heart Relies on Ketone Bodies as a Fuel.

Circulation. 2016 Feb 23;133(8):698-705. doi: 10.1161/CIRCULATIONAHA.115.017355. Epub 2016 Jan 27.

Cardiac ketone body metabolism.

Biochim Biophys Acta Mol Basis Dis. 2020 Jun 1;1866(6):165739. doi: 10.1016/j.bbadis.2020.165739. Epub 2020 Feb 19.

Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure.

Circulation. 2016 Feb 23;133(8):706-16. doi: 10.1161/CIRCULATIONAHA.115.017545. Epub 2016 Jan 27.

Implications of Altered Ketone Metabolism and Therapeutic Ketosis in Heart Failure.

Circulation. 2020 Jun 2;141(22):1800-1812. doi: 10.1161/CIRCULATIONAHA.119.045033. Epub 2020 Jun 1.

Fatty acid and ketone metabolism.

Circulation. 1985 Nov;72(5 Pt 2):IV9-12.

Ketone therapy for heart failure: current evidence for clinical use.

Cardiovasc Res. 2022 Mar 16;118(4):977-987. doi: 10.1093/cvr/cvab068.

Metabolism of the human heart. II. Studies on fat, ketone and amino acid metabolism.

Am J Med. 1954 Apr;16(4):504-15. doi: 10.1016/0002-9343(54)90365-4.

Failing Heart and Starving Brain: Ketone Bodies to the Rescue.

Circulation. 2016 Jul 26;134(4):265-6. doi: 10.1161/CIRCULATIONAHA.116.022141.

引用本文的文献

Metabolic Adaptations and Therapies in Cardiac Hypoxia: Mechanisms and Clinical Implications/ Potential Strategies.

JACC Basic Transl Sci. 2025 Apr 2. doi: 10.1016/j.jacbts.2024.12.008.

Underlying mechanisms of ketotherapy in heart failure: current evidence for clinical implementations.

Front Pharmacol. 2024 Oct 24;15:1463381. doi: 10.3389/fphar.2024.1463381. eCollection 2024.

Comparative Metabolomics in Single Ventricle Patients after Fontan Palliation: A Strong Case for a Targeted Metabolic Therapy.

Metabolites. 2023 Aug 9;13(8):932. doi: 10.3390/metabo13080932.

Does Myocardial Atrophy Represent Anti-Arrhythmic Phenotype?

Biomedicines. 2022 Nov 4;10(11):2819. doi: 10.3390/biomedicines10112819.

Mechanism of reduced muscle atrophy via ketone body (D)-3-hydroxybutyrate.

Cell Biosci. 2022 Jun 20;12(1):94. doi: 10.1186/s13578-022-00826-2.

SGLT2 Inhibitors and Ketone Metabolism in Heart Failure.

J Lipid Atheroscler. 2022 Jan;11(1):1-19. doi: 10.12997/jla.2022.11.1.1. Epub 2022 Jan 13.

Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides.

Front Physiol. 2019 Apr 10;10:382. doi: 10.3389/fphys.2019.00382. eCollection 2019.

The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense.

JCI Insight. 2019 Feb 21;4(4). doi: 10.1172/jci.insight.124079.

Metabolic remodeling of substrate utilization during heart failure progression.

Heart Fail Rev. 2019 Jan;24(1):143-154. doi: 10.1007/s10741-018-9713-0.

Multi-dimensional Roles of Ketone Bodies in Fuel Metabolism, Signaling, and Therapeutics.

Cell Metab. 2017 Feb 7;25(2):262-284. doi: 10.1016/j.cmet.2016.12.022.

本文引用的文献

The Failing Heart Relies on Ketone Bodies as a Fuel.

Circulation. 2016 Feb 23;133(8):698-705. doi: 10.1161/CIRCULATIONAHA.115.017355. Epub 2016 Jan 27.

Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure.

Circulation. 2016 Feb 23;133(8):706-16. doi: 10.1161/CIRCULATIONAHA.115.017545. Epub 2016 Jan 27.

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Heart failure: Ketone bodies as fuel in heart failure.

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