Lach Elliot
Boston Surgical Group, Southborough, MA 01772, USA.
J Cosmet Laser Ther. 2008 Dec;10(4):202-9. doi: 10.1080/14764170802516680.
This study compares the efficacy and safety of low-level, dual-wavelength laser energy and massage with massage alone for the reduction of subcutaneous fat in the thighs of normal women. The device was an early prototype of the FDA-cleared SmoothShapes system (Elemé Medical, Merrimack, NH, USA).
The thighs of each individual (n=102) were randomized to either laser light (dual wavelength of 650+/-20 nm and 915+/-10 nm) and massage or to massage alone (control). Individuals who completed the study (n=74) received a mean of 14.3 treatments over 4-6 weeks. Magnetic resonance imaging (MRI) scans quantified fat pad dimensions before and after the final treatment.
Fat thickness decreased for the leg treated with laser-massage by 1.19 cm(2) (mean) and increased by 3.82 cm(2) (mean) for the control leg over time. The difference was statistically significant (p<0.001). Among those who completed the study, 82.26% responded to treatment. Individuals reported looser-fitting clothing and satisfaction with the procedure and results. Adverse effects were limited to occasional increases in urinary frequency.
Low-level, dual-beam laser energy with massage appears to be safe and more efficacious than massage alone for reducing subcutaneous fat in the thighs of normal women.
本研究比较了低强度双波长激光能量与单纯按摩在减少正常女性大腿皮下脂肪方面的疗效和安全性。该设备是美国食品药品监督管理局（FDA）批准的SmoothShapes系统（Elemé Medical，美国新罕布什尔州梅里马克）的早期原型。
将每位受试者（n = 102）的大腿随机分为接受激光照射（650±20 nm和915±10 nm双波长）加按摩组或单纯按摩组（对照组）。完成研究的受试者（n = 74）在4 - 6周内平均接受了14.3次治疗。通过磁共振成像（MRI）扫描对最终治疗前后的脂肪垫尺寸进行量化。
随着时间推移，接受激光 - 按摩治疗的腿部脂肪厚度平均减少了1.19 cm²，而对照组腿部脂肪厚度平均增加了3.82 cm²。差异具有统计学意义（p < 0.001）。在完成研究的受试者中，82.26%对治疗有反应。受试者报告衣服变宽松，并对治疗过程和结果感到满意。不良反应仅限于偶尔出现的尿频增加。
低强度双光束激光能量结合按摩在减少正常女性大腿皮下脂肪方面似乎比单纯按摩更安全、更有效。
